[HTML][HTML] Prognostic relevance of NPM1, CEBPA, and FLT3 mutations in cytogenetically normal adult AML patients

A Ningombam, D Verma, R Kumar, J Singh… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Acute myeloid leukemia with normal cytogenetics (CN-AML) is the largest
group of AML patients with very heterogenous patient outcomes. The revised World Health …

Mitochondrial gene expression signature predicts prognosis of pediatric acute myeloid leukemia patients

S Chaudhary, S Ganguly, JK Palanichamy… - Frontiers in …, 2023 - frontiersin.org
Introduction Gene expression profile of mitochondrial-related genes is not well deciphered
in pediatric acute myeloid leukaemia (AML). We aimed to identify mitochondria-related …

Association of leukemia and mitochondrial diseases—A review

A Sachdeva, JP Rajguru, K Sohi… - Journal of family …, 2019 - journals.lww.com
Mitochondria play an important role in various metabolic pathways like oxidative
phosphorylation free radical generation and apoptosis. Defects in mitochondrial function are …

Expression of Mitochondrial Long Non-Coding RNAs, MDL1 and MDL1AS, Are Good Prognostic and/or Diagnostic Biomarkers for Several Cancers, Including …

P Garrido, A Casas-Benito, IM Larrayoz… - Cancers, 2024 - mdpi.com
Simple Summary Personalized cancer medicine is based on the right classification of
patients that can, then, be treated according to their specific characteristics. This is …

Polymorphisms and haplotype of mitochondrial DNA D-loop region are associated with polycystic ovary syndrome in a Chinese population

X Deng, D Ji, X Li, Y Xu, Y Cao, W Zou, C Liang… - Mitochondrion, 2021 - Elsevier
Polymorphisms in mitochondrial DNA (mtDNA) have been linked to a range of diseases.
Here we investigate the relationship between mtDNA D-loop region polymorphisms, mtDNA …

BAALC gene expression tells a serious patient outcome tale in NPM1-wild type/FLT3-ITD negative cytogenetically normal-acute myeloid leukemia in adults

D Verma, R Kumar, MS Ali, J Singh, M Arora… - Blood Cells, Molecules …, 2022 - Elsevier
Acute myeloid leukemia with normal cytogenetics (CN-AML) is the largest group of AML
patients which is associated with a variegated patient outcome. Multiple molecular markers …

Mitochondrial biogenesis gene POLG correlates with outcome in pediatric acute myeloid leukemia

S Chaudhary, S Ganguly, A Singh… - Leukemia & …, 2022 - Taylor & Francis
Mitochondrial adaptations, including alterations in mitochondrial DNA (mtDNA) copy
number, respiratory complex activity, and onco-metabolite production, are common in …

Decoding mitochondrial genes in pediatric AML and development of a novel prognostic mitochondrial gene signature

S Chaudhary, S Ganguly, JK Palanichamy, A Singh… - medRxiv, 2022 - medrxiv.org
Background Gene expression profile of mitochondrial-related genes is not well deciphered
in pediatric acute myeloid leukaemia (AML). We aimed to identify mitochondria-related …