The search for noise-induced cochlear synaptopathy in humans: Mission impossible?

N Bramhall, EF Beach, B Epp, CG Le Prell… - Hearing research, 2019 - Elsevier
Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

The relative contribution of cochlear synaptopathy and reduced inhibition to age-related hearing impairment for people with normal audiograms

M Gómez-Álvarez, PT Johannesen… - Trends in …, 2023 - journals.sagepub.com
Older people often show auditory temporal processing deficits and speech-in-noise
intelligibility difficulties even when their audiogram is clinically normal. The causes of such …

Individual differences reveal correlates of hidden hearing deficits

HM Bharadwaj, S Masud, G Mehraei… - Journal of …, 2015 - Soc Neuroscience
Clinical audiometry has long focused on determining the detection thresholds for pure tones,
which depend on intact cochlear mechanics and hair cell function. Yet many listeners with …

Auditory brainstem response latency in noise as a marker of cochlear synaptopathy

G Mehraei, AE Hickox, HM Bharadwaj… - Journal of …, 2016 - Soc Neuroscience
Evidence from animal and human studies suggests that moderate acoustic exposure,
causing only transient threshold elevation, can nonetheless cause “hidden hearing loss” that …

Cochlear neuropathy and the coding of supra-threshold sound

HM Bharadwaj, S Verhulst, L Shaheen… - Frontiers in systems …, 2014 - frontiersin.org
Many listeners with hearing thresholds within the clinically normal range nonetheless
complain of difficulty hearing in everyday settings and understanding speech in noise …

The effects of age and cochlear hearing loss on temporal fine structure sensitivity, frequency selectivity, and speech reception in noise

K Hopkins, BCJ Moore - The Journal of the Acoustical Society of …, 2011 - pubs.aip.org
Temporal fine structure (TFS) sensitivity, frequency selectivity, and speech reception in noise
were measured for young normal-hearing (NHY), old normal-hearing (NHO), and hearing …

Processing of temporal fine structure as a function of age

JH Grose, SK Mamo - Ear and hearing, 2010 - journals.lww.com
Objectives: The purpose of this study was to determine whether the processing of temporal
fine structure diminishes with age, even in the presence of relatively normal audiometric …

Normal hearing is not enough to guarantee robust encoding of suprathreshold features important in everyday communication

D Ruggles, H Bharadwaj… - Proceedings of the …, 2011 - National Acad Sciences
“Normal hearing” is typically defined by threshold audibility, even though everyday
communication relies on extracting key features of easily audible sound, not on sound …

Influence of musical training on understanding voiced and whispered speech in noise

DR Ruggles, RL Freyman, AJ Oxenham - PloS one, 2014 - journals.plos.org
This study tested the hypothesis that the previously reported advantage of musicians over
non-musicians in understanding speech in noise arises from more efficient or robust coding …

A multi-resolution envelope-power based model for speech intelligibility

S Jørgensen, SD Ewert, T Dau - The Journal of the Acoustical Society …, 2013 - pubs.aip.org
The speech-based envelope power spectrum model (sEPSM) presented by Jørgensen and
Dau [(2011). J. Acoust. Soc. Am. 130, 1475–1487] estimates the envelope power signal-to …