European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke

E Berge, W Whiteley, H Audebert… - European stroke …, 2021 - journals.sagepub.com
Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients
with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide …

Risk factors of hemorrhagic transformation in acute ischaemic stroke: A systematic review and meta-analysis

J Sun, C Lam, L Christie, C Blair, X Li… - Frontiers in …, 2023 - frontiersin.org
Background Hemorrhagic transformation (HT) following reperfusion therapies for acute
ischaemic stroke often predicts a poor prognosis. This systematic review and meta-analysis …

[HTML][HTML] Efficacy and safety of clopidogrel and/or aspirin for ischemic stroke/transient ischemic attack: An overview of systematic reviews and meta-analysis

Y Yang, Z Huang, X Zhang - Medicine, 2021 - journals.lww.com
Objective: Patients experiencing acute ischemic stroke or transient ischemic attack are
commonly treated with clopidogrel and/or aspirin (mono-and dual-antiplatelet therapy) to …

A nanomule peptide carrier delivers siRNA across the intact blood-brain barrier to attenuate ischemic stroke

BA Eyford, CSB Singh, T Abraham, L Munro… - Frontiers in Molecular …, 2021 - frontiersin.org
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment
of neuroinflammation (NI) of the central nervous system. A twelve-amino acid peptide that …

Safety and efficacy of dual antiplatelet pretreatment in patients with ischemic stroke treated with IV thrombolysis: a systematic review and meta-analysis

K Malhotra, AH Katsanos, N Goyal, N Ahmed… - Neurology, 2020 - AAN Enterprises
Objective Conflicting data exist on the safety and efficacy of IV thrombolysis (IVT) in patients
with acute ischemic stroke (AIS) receiving dual antiplatelet pretreatment (DAPP). The aim of …

Safety and efficacy of oral antiplatelet for patients who had acute ischaemic stroke undergoing endovascular therapy

X Huo, J Jing, A Wang, D Mo, F Gao, N Ma… - Stroke and Vascular …, 2021 - svn.bmj.com
Background and purpose To investigate the safety and efficacy of oral antiplatelet therapy
(APT) for patients who had acute ischaemic stroke (AIS), receiving endovascular therapy …

The pivotal role of timing of intravenous thrombolysis bridging treatment prior to endovascular thrombectomy

J Molad, H Hallevi, E Seyman… - Therapeutic …, 2023 - journals.sagepub.com
Background: The role of intravenous thrombolysis (IVT) as bridging treatment prior to
endovascular thrombectomy (EVT) is under debate and better patient selection is needed …

Prospective pilot study of tirofiban in progressive stroke after intravenous thrombolysis

Y Zhang, J Wang, Z Ma, G Mu, D Liang, Y Li… - Frontiers in …, 2022 - frontiersin.org
Background Intravenous thrombolysis (IVT) is a standard procedure for the treatment of
patients with acute ischemic stroke (AIS). Improving the therapeutic efficacy of IVT is an …

Safety and efficacy of antiplatelet use before intravenous thrombolysis for acute ischemic stroke

A Mowla, M Sharifian-Dorche, S Mehla, NS Lail… - Journal of the …, 2021 - Elsevier
Aim To study the effects of pretreatment with Antiplatelet (AP) before IV thrombolysis (IVT) on
the rate of symptomatic intracranial hemorrhage (sICH) and functional outcome in patients …

Management of stroke in patients on antithrombotic therapy: Practical issues in the era of direct oral anticoagulants

I Sibon, JS Liegey - Revue Neurologique, 2022 - Elsevier
Antithrombotic drugs (ADs) are the mainstay of secondary prevention of thrombotic vascular
diseases. Management of patients under long-term treatment with ADs admitted for acute …