Interactions between Borrelia burgdorferi and ticks
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …
Lyme disease in humans
JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …
Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …
burgdorferi, has risen from relative obscurity to become a global public health problem and a …
Tick microbiome: the force within
S Narasimhan, E Fikrig - Trends in parasitology, 2015 - cell.com
Ticks are obligate blood-feeders and serve as vectors of human and livestock pathogens
worldwide. Defining the tick microbiome and deciphering the interactions between the tick …
worldwide. Defining the tick microbiome and deciphering the interactions between the tick …
Gut microbiota of the tick vector Ixodes scapularis modulate colonization of the Lyme disease spirochete
Arthopods such as Ixodes scapularis ticks serve as vectors for many human pathogens. The
arthropod gut presents a pivotal microbial entry point and determines pathogen colonization …
arthropod gut presents a pivotal microbial entry point and determines pathogen colonization …
Interaction of the tick immune system with transmitted pathogens
O Hajdušek, R Šíma, N Ayllón, M Jalovecká… - Frontiers in cellular …, 2013 - frontiersin.org
Ticks are hematophagous arachnids transmitting a wide variety of pathogens including
viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to …
viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to …
Tick immune system: what is known, the interconnections, the gaps, and the challenges
AC Fogaça, G Sousa, DB Pavanelo, E Esteves… - Frontiers in …, 2021 - frontiersin.org
Ticks are ectoparasitic arthropods that necessarily feed on the blood of their vertebrate
hosts. The success of blood acquisition depends on the pharmacological properties of tick …
hosts. The success of blood acquisition depends on the pharmacological properties of tick …
Lyme disease: a rigorous review of diagnostic criteria and treatment
AT Borchers, CL Keen, AC Huntley… - Journal of autoimmunity, 2015 - Elsevier
Lyme disease was originally identified in Lyme, Connecticut, based upon an unusual cluster
of what appeared to be patients with juvenile rheumatoid arthritis. It was subsequently …
of what appeared to be patients with juvenile rheumatoid arthritis. It was subsequently …
The unique paradigm of spirochete motility and chemotaxis
Spirochete motility is enigmatic: It differs from the motility of most other bacteria in that the
entire bacterium is involved in translocation in the absence of external appendages. Using …
entire bacterium is involved in translocation in the absence of external appendages. Using …
Gene Regulation in Borrelia burgdorferi
DS Samuels - Annual review of microbiology, 2011 - annualreviews.org
Borrelia burgdorferi, the spirochete that causes Lyme disease, is maintained in nature via an
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …