Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …

Ticks are obligate blood-feeders and serve as vectors of human and livestock pathogens
worldwide. Defining the tick microbiome and deciphering the interactions between the tick …

Arthopods such as Ixodes scapularis ticks serve as vectors for many human pathogens. The
arthropod gut presents a pivotal microbial entry point and determines pathogen colonization …

Ticks are hematophagous arachnids transmitting a wide variety of pathogens including
viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to …

Ticks are ectoparasitic arthropods that necessarily feed on the blood of their vertebrate
hosts. The success of blood acquisition depends on the pharmacological properties of tick …

Lyme disease was originally identified in Lyme, Connecticut, based upon an unusual cluster
of what appeared to be patients with juvenile rheumatoid arthritis. It was subsequently …

Spirochete motility is enigmatic: It differs from the motility of most other bacteria in that the
entire bacterium is involved in translocation in the absence of external appendages. Using …

Borrelia burgdorferi, the spirochete that causes Lyme disease, is maintained in nature via an
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …