Peroxisome proliferator-activated receptors (PPARs) as therapeutic target in neurodegenerative disorders

S Agarwal, A Yadav, RK Chaturvedi - Biochemical and biophysical …, 2017 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and they serve to
be a promising therapeutic target for several neurodegenerative disorders, which includes …

Neuroprotective mechanisms of plant extracts against MPTP induced neurotoxicity: Future applications in Parkinson's disease

AI Abushouk, A Negida, H Ahmed… - Biomedicine & …, 2017 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease, affecting about seven to 10 million patients worldwide. The major …

Recent advances in herbal medicines treating Parkinson's disease

X Li, S Zhang, S Liu, F Lu - Fitoterapia, 2013 - Elsevier
Herbal medicines have attracted considerable attention in recent years, which are used to
treat Parkinson's disease (PD) in China based on traditional Chinese medicine or modern …

[HTML][HTML] Neuroprotective effects of a standardized flavonoid extract from safflower against a rotenone-induced rat model of Parkinson's disease

N Ablat, D Lv, R Ren, Y Xiaokaiti, X Ma, X Zhao, Y Sun… - Molecules, 2016 - mdpi.com
Parkinson's disease (PD) is a major age-related neurodegenerative disorder characterized
by the loss of dopaminergic neurons in the substantia nigra par compacta (SNpc). Rotenone …

Anti-Parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models?

JX Song, SCW Sze, TB Ng, CKF Lee… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Herbal medicines are used to treat Parkinson's
disease (PD) in ancient medical systems in Asian countries such as India, China, Japan and …

Autophagy modulators from traditional Chinese medicine: Mechanisms and therapeutic potentials for cancer and neurodegenerative diseases

SF Wang, MY Wu, CZ Cai, M Li, JH Lu - Journal of ethnopharmacology, 2016 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese medicine (TCM), an ancient
yet still alive medicinal system widely used in East Asia, has played an essential role in …

[HTML][HTML] Protective effects and mechanism of radix polygalae against neurological diseases as well as effective substance

N Jiang, S Wei, Y Zhang, W He, H Pei, H Huang… - Frontiers in …, 2021 - frontiersin.org
Radix Polygalae (also known as Yuanzhi in China) is the dried rhizome of Polygala
tenuifolia Willd. or Polygala sibirica L., which is a famous Chinese herb and has been widely …

[HTML][HTML] Neuroprotective effect of chebulagic acid via autophagy induction in SH-SY5Y cells

HJ Kim, J Kim, KS Kang, KT Lee… - Biomolecules & …, 2014 - ncbi.nlm.nih.gov
Autophagy is a series of catabolic process mediating the bulk degradation of intracellular
proteins and organelles through formation of a double-membrane vesicle, known as an …

[HTML][HTML] Neuroprotective effects of Tongtian oral liquid, a Traditional Chinese Medicine in the Parkinson's disease-induced zebrafish model

S Dongjie, RS Rajendran, Q Xia, G She, P Tu… - Biomedicine & …, 2022 - Elsevier
Traditional Chinese medicine (TCM) is used in the treatment of Parkinson's disease (PD)
worldwide. Tongtian Oral Liquid (TTKFY) is one such patented TCM, and a poly-herbal …

Effects of the root bark of Paeonia suffruticosa on mitochondria-mediated neuroprotection in an MPTP-induced model of Parkinson's disease

HG Kim, G Park, Y Piao, MS Kang, YK Pak… - Food and Chemical …, 2014 - Elsevier
Parkinson's disease (PD) is generally characterized by the progressive loss of dopaminergic
neurons projecting from the substantia nigra pars compacta (SNpc) to the striatum that …