Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Traditional orthopedic metal implants, such as titanium (Ti), Ti alloys, and cobalt-chromium
(Co-Cr) alloys, cannot be degraded in vivo. Fracture patients is must always suffer a second …

The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

Tumor growth and metastasis rely on tumor vascular network for the adequate supply of
oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth …

The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million
people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is …

Extracellular vesicles have shown good potential in disease treatments including ischemic
injury such as myocardial infarction. However, the efficient production of highly active …

Bioactive glasses are reported to be able to stimulate more bone regeneration than other
bioactive ceramics but they lag behind other bioactive ceramics in terms of commercial …

Tissue-resident macrophages can self-maintain without contribution of adult hematopoiesis.
Herein we show that tissue-resident interstitial macrophages (Res-TAMs) in mouse lungs …

Tumor relapse after chemotherapy-induced regression is a major clinical problem, because
it often involves inoperable metastatic disease. Tumor-associated macrophages (TAM) are …

Monocytes and macrophages play a critical role in tissue development, homeostasis, and
injury repair. These innate immune cells participate in guiding vascular remodeling …