COVID-19 vaccination: The road ahead
DM Altmann, RJ Boyton - Science, 2022 - science.org
A diverse array of successful, first-generation SARS-CoV-2 vaccines have played a huge
role in efforts to bring the COVID-19 pandemic under control, even though inequitable …
role in efforts to bring the COVID-19 pandemic under control, even though inequitable …
T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
Viral persistence, reactivation, and mechanisms of long COVID
The COVID-19 global pandemic caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has infected hundreds of millions of individuals …
coronavirus 2 (SARS-CoV-2) infection has infected hundreds of millions of individuals …
[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …
fundamental components of the adaptive immune system are B cells (the source of …
Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival
S Dispinseri, M Secchi, MF Pirillo, M Tolazzi… - Nature …, 2021 - nature.com
Understanding how antibody responses to SARS-CoV-2 evolve during infection may
provide important insight into therapeutic approaches and vaccination for COVID-19. Here …
provide important insight into therapeutic approaches and vaccination for COVID-19. Here …
SARS-CoV-2 vaccination induces mucosal antibody responses in previously infected individuals
K Sano, D Bhavsar, G Singh, D Floda… - Nature …, 2022 - nature.com
Immune responses at the respiratory mucosal interface are critical to prevent respiratory
infections but it is unclear to what extent antigen specific mucosal secretory IgA (SIgA) …
infections but it is unclear to what extent antigen specific mucosal secretory IgA (SIgA) …
Immunology of SARS-CoV-2 infection in children
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission
A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena… - Cell host & …, 2022 - cell.com
SARS-CoV-2 lineages have diverged into highly prevalent variants termed" variants of
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …
[HTML][HTML] SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2
In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast-
derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …
derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies
Several variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have
emerged during the current coronavirus disease 2019 (COVID-19) pandemic. Although …
emerged during the current coronavirus disease 2019 (COVID-19) pandemic. Although …