[HTML][HTML] Oxidative stress: a key modulator in neurodegenerative diseases
Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …
Inflammation in CNS neurodegenerative diseases
J Stephenson, E Nutma, P van der Valk, S Amor - Immunology, 2018 - Wiley Online Library
Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …
increased attention as they impose a considerable socioeconomic impact, due in part to the …
Selective vulnerability in neurodegenerative diseases
Neurodegenerative diseases have two general characteristics that are so fundamental we
usually take them for granted. The first is that the pathology associated with the disease only …
usually take them for granted. The first is that the pathology associated with the disease only …
[HTML][HTML] In vitro Models of Neurodegenerative Diseases
A Slanzi, G Iannoto, B Rossi, E Zenaro… - Frontiers in cell and …, 2020 - frontiersin.org
Neurodegenerative diseases are progressive degenerative conditions characterized by the
functional deterioration and ultimate loss of neurons. These incurable and debilitating …
functional deterioration and ultimate loss of neurons. These incurable and debilitating …
Mitochondrial dysfunction in the development and progression of neurodegenerative diseases
J Johnson, E Mercado-Ayon, Y Mercado-Ayon… - Archives of biochemistry …, 2021 - Elsevier
In addition to ATP synthesis, mitochondria are highly dynamic organelles that modulate
apoptosis, ferroptosis, and inflammasome activation. Through executing these varied …
apoptosis, ferroptosis, and inflammasome activation. Through executing these varied …
Neurodegenerative diseases and effective drug delivery: A review of challenges and novel therapeutics
The central nervous system (CNS) encompasses the brain and spinal cord and is
considered the processing center and the most vital part of human body. The central …
considered the processing center and the most vital part of human body. The central …
Apoptosis and its therapeutic implications in neurodegenerative diseases
NS Erekat - Clinical Anatomy, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by progressive loss of particular populations
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
[HTML][HTML] Programmed cell death in diabetic nephropathy: a review of apoptosis, autophagy, and necroptosis
NS Erekat - Medical Science Monitor: International Medical Journal …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy is a common complication of type I and type II diabetes, in which renal
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …
[HTML][HTML] Role of SNAREs in neurodegenerative diseases
A Margiotta - Cells, 2021 - mdpi.com
Neurodegenerative diseases are pathologies of the central and peripheral nervous systems
characterized by loss of brain functions and problems in movement which occur due to the …
characterized by loss of brain functions and problems in movement which occur due to the …
[HTML][HTML] Research progress on multiple cell death pathways of podocytes in diabetic kidney disease
C Yang, Z Zhang, J Liu, P Chen, J Li, H Shu, Y Chu… - Molecular …, 2023 - Springer
Diabetic kidney disease (DKD) is the main cause of end-stage renal disease, and its clinical
manifestations are progressive proteinuria, decreased glomerular filtration rate, and renal …
manifestations are progressive proteinuria, decreased glomerular filtration rate, and renal …