Checkpoint inhibitors and anti-angiogenic agents: A winning combination

P Brest, B Mograbi, G Pagès, P Hofman… - British Journal of …, 2023 - nature.com
The combination of immune checkpoint inhibitors and anti-angiogenic agents is a promising
new approach in cancer treatment. Immune checkpoint inhibitors block the signals that help …

Soluble biomarkers to predict clinical outcomes in non-small cell lung cancer treated by immune checkpoints inhibitors

J Ancel, V Dormoy, BN Raby, V Dalstein… - Frontiers in …, 2023 - frontiersin.org
Lung cancer remains the first cause of cancer-related death despite many therapeutic
innovations, including immune checkpoint inhibitors (ICI). ICI are now well used in daily …

Efficacy and response biomarkers of apatinib in the treatment of malignancies in China: a review

Z Tian, X Niu, W Yao - Frontiers in Oncology, 2021 - frontiersin.org
Apatinib is a multitarget tyrosine kinase inhibitor marketed in China for the treatment of
advanced gastric cancer (GC) and hepatocellular carcinoma (HCC). It has also been used …

Research advances in mechanism of antiangiogenic therapy combined with immune checkpoint inhibitors for treatment of non-small cell lung cancer

D He, L Wang, J Xu, J Zhao, H Bai, J Wang - Frontiers in Immunology, 2023 - frontiersin.org
Immunotherapy has changed the treatment strategy of non-small cell lung cancer (NSCLC)
in recent years, among which anti-PD-1/PD-L1 antibodies are the most used. However, the …

[HTML][HTML] Biomarkers for predicting the efficacy of immune checkpoint inhibitors

C Wang, H Wang, L Wang - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
Immune checkpoint blockade has vastly changed the landscape of cancer treatment and
showed a promising prognosis for cancer patients. However, there is still a large portion of …

Hyperprogressive disease: main features and key controversies

H Arasanz, M Zuazo, A Bocanegra, L Chocarro… - International journal of …, 2021 - mdpi.com
Along with the positioning of immunotherapy as a preferential treatment for a wide variety of
neoplasms, a new pattern of response consisting in a sudden acceleration of tumor growth …

Current progress of immune checkpoint inhibitors in the treatment of advanced hepatocellular carcinoma

X Yin, T Wu, Y Lan, W Yang - Bioscience Reports, 2022 - portlandpress.com
Hepatocellular carcinoma (HCC) is the most common primary liver cancer worldwide. The
onset of the disease is occult and develops rapidly. As a result, the disease is often detected …

Liquid biopsy and Immuno-Oncology for advanced nonsmall cell lung cancer

L Sinoquet, W Jacot, X Quantin… - Clinical …, 2023 - academic.oup.com
Background In the last decade, immune checkpoint inhibitors have revolutionized the
treatment of metastatic nonsmall cell lung cancer without oncogenic addiction. Currently …

The role of circulating tumor DNA in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

H Wang, F Zhou, M Qiao, X Li, C Zhao, L Cheng… - Frontiers in …, 2021 - frontiersin.org
Background The use of circulating tumor DNA (ctDNA) to reflect clinical benefits of advanced
non-small cell lung cancer (NSCLC) patients during immune checkpoint inhibitor (ICI) …

Smoking status combined with tumor mutational burden as a prognosis predictor for combination immune checkpoint inhibitor therapy in non‐small cell lung cancer

LY Sun, WJ Cen, WT Tang, YK Long, XH Yang… - Cancer …, 2021 - Wiley Online Library
Background This study aimed to explore the prognostic value of tumor mutational burden
(TMB) combined with smoking status in advanced non‐small cell lung cancer (NSCLC) …