Challenges in diagnosis and understanding of natural history of polycystic ovary syndrome

AE Joham, T Piltonen, ME Lujan… - Clinical …, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting 8%–13%
of reproductive‐aged women. The aetiology of the syndrome is complex, with genetic …

Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity and treatment with metformin and GLP-1s

A Etrusco, M Mikuš, A D'Amato, F Barra, P Planinić… - Biomedicines, 2024 - mdpi.com
Background: The purpose of this narrative review is to describe the mechanisms that are
responsible for the development of infertility and PCOS, with a focus on the role of obesity …

A “one‐stop shop” decision tree for diagnosing and phenotyping polycystic ovarian syndrome on serum metabolic fingerprints

R Wang, Z Gu, Y Wang, X Yin, W Liu… - Advanced Functional …, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is a common endocrine disease regulated by metabolic
disorders, the effective intervention of which depends on diverse phenotypes (eg, insulin …

Polycystic ovary syndrome fuels cardiovascular inflammation and aggravates ischemic cardiac injury

L Gao, Y Zhao, H Wu, X Lin, F Guo, J Li, Y Long… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Reducing cardiovascular disease burden among women remains
challenging. Epidemiologic studies have indicated that polycystic ovary syndrome (PCOS) …

Effects of Bu Shen Hua Zhuo formula on the LPS/TLR4 pathway and gut microbiota in rats with letrozole-induced polycystic ovary syndrome

Y Wang, H Xiao, Y Liu, Q Tong, Y Yu, B Qi… - Frontiers in …, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
gynecology. Traditional Chinese medicine (TCM) is widely used for the treatment of PCOS in …

Risk of type 2 diabetes mellitus in polycystic ovary syndrome is associated with obesity: a meta-analysis of observational studies

P Anagnostis, RD Paparodis, JK Bosdou, C Bothou… - Endocrine, 2021 - Springer
Purpose The exact risk of type 2 diabetes mellitus (T2DM) in women with polycystic ovary
syndrome (PCOS) is unknown. It is also unclear if obesity independently increases T2DM …

Body mass index and polycystic ovary syndrome: a 2-sample bidirectional Mendelian randomization study

Y Zhao, Y Xu, X Wang, L Xu, J Chen… - The Journal of …, 2020 - academic.oup.com
Background Observational studies have shown a link between elevated body mass index
(BMI) and the risk of polycystic ovary syndrome (PCOS). While Mendelian randomization …

Polycystic Ovary Syndrome: pathophysiology and controversies in diagnosis

D Fahs, D Salloum, M Nasrallah, G Ghazeeri - Diagnostics, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder that commonly
affects women in the reproductive age group. The disorder has features that propose a …

Regulation of Insulin Resistance, Lipid Profile and Glucose Metabolism Associated with Polycystic Ovary Syndrome by Tinospora cordifolia

R Rani, HR Chitme, N Kukreti, P Pant… - Nutrients, 2023 - mdpi.com
Background: The plant Tinospora cordifolia (TC), traditionally known as guduchi or giloy, is
used for a number of health conditions as a nutritional supplement and rejuvenation …

The role of individually selected diets in obese women with PCOS—a review

I Chudzicka-Strugała, I Gołębiewska, B Banaszewska… - Nutrients, 2022 - mdpi.com
Polycystic ovarian syndrome (PCOS) is one of the most common heterogeneous endocrine
and metabolic disorders in premenopausal women. It is a complex multifactorial disorder …