A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options

A Garakani, JW Murrough, RC Freire, RP Thom… - Frontiers in …, 2020 - frontiersin.org
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

[HTML][HTML] Amygdala circuit substrates for stress adaptation and adversity

WH Zhang, JY Zhang, A Holmes, BX Pan - Biological psychiatry, 2021 - Elsevier
Brain systems that promote the maintenance of homeostasis in face of stress have
significant adaptive value. A growing body of work across species demonstrates a critical …

Neuroimaging in social anxiety disorder—a meta-analytic review resulting in a new neurofunctional model

AB Bruehl, A Delsignore, K Komossa… - … & Biobehavioral Reviews, 2014 - Elsevier
Social anxiety disorder (SAD) is one of the most frequent anxiety disorders. The landmark
meta-analysis of functional neuroimaging studies by Etkin and Wager (2007) revealed …

Structural and functional deficits and couplings in the cortico-striato-thalamo-cerebellar circuitry in social anxiety disorder

X Zhang, X Suo, X Yang, H Lai, N Pan, M He… - Translational …, 2022 - nature.com
Although functional and structural abnormalities in brain regions involved in the
neurobiology of fear and anxiety have been observed in patients with social anxiety disorder …

Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report

JAS Crippa, GN Derenusson… - Journal of …, 2011 - journals.sagepub.com
Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis,
has anxiolytic properties. However, no study to date has investigated the effects of this …

The impact of mindfulness-based interventions on brain activity: A systematic review of functional magnetic resonance imaging studies

KS Young, AM van der Velden, MG Craske… - Neuroscience & …, 2018 - Elsevier
Mindfulness-based interventions are increasingly used in the treatment and prevention of
mental health conditions. Despite this, the mechanisms of change for such interventions are …

Animal models of social avoidance and social fear

I Toth, ID Neumann - Cell and tissue research, 2013 - Springer
Social fear and avoidance of social situations represent the main behavioral symptoms of
social anxiety disorder (SAD), a highly prevalent anxiety disorder that is poorly elucidated …

Brain connectomics predict response to treatment in social anxiety disorder

S Whitfield-Gabrieli, SS Ghosh, A Nieto-Castanon… - Molecular …, 2016 - nature.com
We asked whether brain connectomics can predict response to treatment for a
neuropsychiatric disorder better than conventional clinical measures. Pre-treatment resting …

Biological markers for anxiety disorders, OCD and PTSD–a consensus statement. Part I: neuroimaging and genetics

B Bandelow, D Baldwin, M Abelli… - The World Journal of …, 2016 - Taylor & Francis
Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that
are specific to certain disorders or syndromes. The objective of this paper is to summarise …