Calcium (Ca2+) is a major second messenger in cells and is essential for the fate and
survival of all higher organisms. Different Ca2+ channels, pumps, or exchangers regulate …

Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

The maturation of human pluripotent stem cell (hPSC)-derived neurons mimics the
protracted timing of human brain development, extending over months to years for reaching …

The divalent cation calcium (Ca2+) is considered one of the main second messengers
inside cells and acts as the most prominent signal in a plethora of biological processes. Its …

Changes of the electrical charges across the surface cell membrane are absolutely
necessary to maintain cellular homeostasis in physiological as well as in pathological …

Calcium (Ca2+) can regulate a wide variety of cellular fates, such as proliferation, apoptosis,
and autophagy. More importantly, changes in the intracellular Ca2+ level can modulate …

Calcium signaling plays important roles in physiological and pathological conditions,
including cutaneous melanoma, the most lethal type of skin cancer. Intracellular calcium …

The maturation of human pluripotent stem cell (hPSC)-derived neurons mimics the
protracted timing of human brain development, extending over months and years to reach …

T-type calcium channels are involved in a multitude of cellular processes, both physiological
and pathological, including cancer. T-type channels are also often aberrantly expressed in …

Although voltage-activated Ca2+ channels are a common feature in excitable cells, their
expression in cancer tissue is less understood. T-type Ca2+ channels are particularly …