Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain

NE Clark, A Katolik, P Gallant, A Welch… - Journal of Biological …, 2023 - ASBMB
In eukaryotic cells, the introns are excised from pre-mRNA by the spliceosome. These
introns typically have a lariat configuration due to the 2′-5′ phosphodiester bond between …

[PDF][PDF] of the thesis Investigations of Noncanonical Nucleic Acids

Z Zhang - J. Phys. Chem. B, 2021 - is.muni.cz
Noncanonical nucleic acid structures, which play crucial roles in a variety of biological
processes, deserve in-depth investigations. Molecular Dynamics (MD) simulations have …