Shedding light on thyroid hormone disorders and Parkinson disease pathology: mechanisms and risk factors
Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of
dopaminergic neurons. Dopaminergic system is interconnected with the hypothalamic …
dopaminergic neurons. Dopaminergic system is interconnected with the hypothalamic …
Receptor modulators associated with the hypothalamus-pituitary-thyroid axis
X Cheng, H Zhang, S Guan, Q Zhao… - Frontiers in …, 2023 - frontiersin.org
The hypothalamus-pituitary-thyroid (HPT) axis maintains normal metabolic balance and
homeostasis in the human body through positive and negative feedback regulation. Its main …
homeostasis in the human body through positive and negative feedback regulation. Its main …
A scientometric analysis and visualization of research on Parkinson's disease associated with pesticide exposure
The etiology and pathogenesis of Parkinson's disease (PD) have not yet been clearly
described. Both genetic and environmental factors contribute to the onset and progression of …
described. Both genetic and environmental factors contribute to the onset and progression of …
Contra-directional expression of plasma superoxide dismutase with lipoprotein cholesterol and high-sensitivity C-reactive protein as important markers of Parkinson's …
W Yang, Z Chang, R Que, G Weng, B Deng… - Frontiers in aging …, 2020 - frontiersin.org
Aim: Oxidative stress and inflammation play critical roles in the neuropathogenesis of PD.
We aimed to evaluate oxidative stress and inflammation status by measuring serum …
We aimed to evaluate oxidative stress and inflammation status by measuring serum …
Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement
IO Ishola, IO Awogbindin, TG Olubodun-Obadun… - Brain Research, 2022 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
both motor and non-motor functions. It is well reported that the neuropathological process …
both motor and non-motor functions. It is well reported that the neuropathological process …
Screening of Monoamine Oxidase B Inhibitors from Fragaria nubicola by Ligand Fishing and Their Neuroprotective Effects
YK Hu, YM Liu, XL Bai, C Ma, X Liao - Journal of Agricultural and …, 2022 - ACS Publications
Fragaria nubicola, known as Tibetan strawberry, is an edible plant possessing various
health-promoting effects. However, its functional compositions were rarely studied. In this …
health-promoting effects. However, its functional compositions were rarely studied. In this …
[HTML][HTML] Improvement of non-motor and motor behavioral alterations associated with Parkinson-like disease in Drosophila melanogaster: Comparative effects of …
MR Poetini, EAS Musachio, SM Araujo, VC Bortolotto… - NeuroToxicology, 2022 - Elsevier
Non-motor alterations such as anxiety and memory deficit may represent early indications of
Parkinson's disease (PD), and therapeutic strategies that reduce non-motor alterations are …
Parkinson's disease (PD), and therapeutic strategies that reduce non-motor alterations are …
Legumain knockout improved cognitive impairment via reducing neuroinflammation in right unilateral common carotid artery occlusion mice
X Chai, X Li, W Zhang, X Tan, H Wang, Z Yang - Life sciences, 2021 - Elsevier
Aims Chronic cerebral hypoperfusion (CCH) is a state of chronic cerebral blood flow
reduction, and it is the main cause of cognitive impairment and neurodegenerative diseases …
reduction, and it is the main cause of cognitive impairment and neurodegenerative diseases …
Biochemical and physiological insights into TRH receptor-mediated signaling
R Trubacova, Z Drastichova, J Novotny - Frontiers in Cell and …, 2022 - frontiersin.org
Thyrotropin-releasing hormone (TRH) is an important endocrine agent that regulates the
function of cells in the anterior pituitary and the central and peripheral nervous systems. By …
function of cells in the anterior pituitary and the central and peripheral nervous systems. By …
Target enzymes considered for the treatment of Alzheimer's disease and Parkinson's disease
Various amyloidogenic proteins have been suggested to be involved in the onset and
progression of neurodegenerative diseases (ND) such as Alzheimer's disease (AD) and …
progression of neurodegenerative diseases (ND) such as Alzheimer's disease (AD) and …