Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training
B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …
exercise training are a potent stimulus for physiological adaptation in many organs …
[HTML][HTML] Interconnections between circadian clocks and metabolism
Circadian rhythms evolved through adaptation to daily light/dark changes in the
environment; they are believed to be regulated by the core circadian clock interlocking …
environment; they are believed to be regulated by the core circadian clock interlocking …
[HTML][HTML] Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study
There is a growing interest in the role of timing of daily behaviors in improving health.
However, little is known about the optimal timing of physical activity to maximize health …
However, little is known about the optimal timing of physical activity to maximize health …
Organism-wide, cell-type-specific secretome mapping of exercise training in mice
There is a significant interest in identifying blood-borne factors that mediate tissue crosstalk
and function as molecular effectors of physical activity. Although past studies have focused …
and function as molecular effectors of physical activity. Although past studies have focused …
Daytime-restricted feeding enhances running endurance without prior exercise in mice
H Xin, R Huang, M Zhou, J Chen, J Zhang, T Zhou… - Nature …, 2023 - nature.com
Physical endurance and energy conservation are essential for survival in the wild. However,
it remains unknown whether and how meal timing regulates physical endurance and muscle …
it remains unknown whether and how meal timing regulates physical endurance and muscle …
[HTML][HTML] Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis
Tissue sensitivity and response to exercise vary according to the time of day and alignment
of circadian clocks, but the optimal exercise time to elicit a desired metabolic outcome is not …
of circadian clocks, but the optimal exercise time to elicit a desired metabolic outcome is not …
Circadian rhythms, disease and chronotherapy
Circadian clocks are biological timing mechanisms that generate 24-h rhythms of physiology
and behavior, exemplified by cycles of sleep/wake, hormone release, and metabolism. The …
and behavior, exemplified by cycles of sleep/wake, hormone release, and metabolism. The …
[HTML][HTML] Time of exercise specifies the impact on muscle metabolic pathways and systemic energy homeostasis
While the timing of food intake is important, it is unclear whether the effects of exercise on
energy metabolism are restricted to unique time windows. As circadian regulation is key to …
energy metabolism are restricted to unique time windows. As circadian regulation is key to …
Circadian clocks in the digestive system
A Segers, I Depoortere - Nature Reviews Gastroenterology & …, 2021 - nature.com
Many molecular, physiological and behavioural processes display distinct 24-hour rhythms
that are directed by the circadian system. The master clock, located in the suprachiasmatic …
that are directed by the circadian system. The master clock, located in the suprachiasmatic …
[HTML][HTML] AICAr, a widely used AMPK activator with important AMPK-independent effects: a systematic review
5-Aminoimidazole-4-carboxamide ribonucleoside (AICAr) has been one of the most
commonly used pharmacological modulators of AMPK activity. The majority of early studies …
commonly used pharmacological modulators of AMPK activity. The majority of early studies …