Low-cost whole-genome assembly has enabled the collection of haplotype-resolved
pangenomes for numerous organisms. In turn, this technological change is encouraging the …

Over the past 25 years, the powerful combination of genome sequencing and bioinformatics
analysis has played a crucial role in interpreting information encoded in bacterial genomes …

Large-scale population genomic surveys are essential to explore the phenotypic diversity of
natural populations. Here we report the whole-genome sequencing and phenotyping of …

Reference genomes guide our interpretation of DNA sequence data. However, conventional
linear references represent only one version of each locus, ignoring variation in the …

Pangenomes provide access to an accurate representation of the genetic diversity of
species, both in terms of sequence polymorphisms and structural variants (SVs). Here we …

Eukaryotic genomes are generally organized in multiple chromosomes. Here we have
created a functional single-chromosome yeast from a Saccharomyces cerevisiae haploid …

Purpose Social media is still influencing consumers and is extending social commerce (S-
Commerce) use. Different social media activities can influence the users' trust and e …

Structural variants (SVs) remain challenging to represent and study relative to point
mutations despite their demonstrated importance. We show that variation graphs, as …

Motivation Pangenome variation graphs model the mutual alignment of collections of DNA
sequences. A set of pairwise alignments implies a variation graph, but there are no scalable …

Domestication refers to artificial selection and breeding of wild species to obtain cultivated
variants that thrive in man-made niches and meet human or industrial requirements. Several …