Abstract Glutathione (GSH; γ-glutamyl-cysteinyl-glycine) is a small intracellular thiol
molecule which is considered as a strong non-enzymatic antioxidant. Glutathione regulates …

The most prominent ion channel localized in plant vacuoles is the slow activating SV type.
Slow vacuolar (SV) channels were discovered by patch clamp studies as early as 1986. In …

Plants exhibit rapid, systemic signaling systems that allow them to coordinate physiological
and developmental responses throughout the plant body, even to highly localized and …

Two-pore channels (TPCs) comprise a subfamily (TPC1–3) of eukaryotic voltage-and ligand-
gated cation channels, with two non-equivalent tandem pore-forming subunits that dimerize …

The two alkali cations Na+ and K+ have similar relative abundances in the earth crust but
display very different distributions in the biosphere. In all living organisms, K+ is the major …

This review portrays the plant vacuole as both a source and a target of Ca2+ signals. In
plants, the vacuole represents a Ca2+ store of enormous size and capacity. Total and free …

The central vacuole is the largest Ca2+ store in a mature plant cell. Ca2+ release from this
store contributes to Ca2+-mediated intracellular signalling in a variety of physiological …

Vacuoles play various roles in many physiologically relevant processes in plants. Some of
the more prominent are turgor provision, the storage of minerals and nutrients, and cellular …

Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and
plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo …

In eukaryotes, two‐pore channels (TPC 1–3) comprise a family of ion channels that regulate
the conductance of Na+ and Ca2+ ions across cellular membranes. TPC 1–3 form …