Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …
miRNAs as Cornerstones in Chronic Lymphocytic Leukemia Pathogenesis and Therapeutic Resistance–An emphasis on the interaction of signaling pathways
Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia.
Patients of advanced age are more likely to develop the condition, which has a highly varied …
Patients of advanced age are more likely to develop the condition, which has a highly varied …
The potential role of miRNAs in the pathogenesis of salivary gland cancer–A Focus on signaling pathways interplay
Salivary gland cancer (SGC) is immensely heterogeneous, both in terms of its physical
manifestation and its aggressiveness. Developing a novel diagnostic and prognostic …
manifestation and its aggressiveness. Developing a novel diagnostic and prognostic …
STAT3 inhibitors: a novel insight for anticancer therapy of pancreatic cancer
X Li, W Jiang, S Dong, W Li, W Zhu, W Zhou - Biomolecules, 2022 - mdpi.com
The signal transducer and activator of transcription (STAT) is a family of intracellular
cytoplasmic transcription factors involved in many biological functions in mammalian signal …
cytoplasmic transcription factors involved in many biological functions in mammalian signal …
The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
A Bogaczyk, I Zawlik, T Zuzak, M Kluz… - International Journal of …, 2023 - mdpi.com
Endometrial cancer is one of the most common cancers in developing and developed
countries. Although the detection of this cancer is high at the early stages, there is still a lack …
countries. Although the detection of this cancer is high at the early stages, there is still a lack …
Pathological role of inflammation in ocular disease progress and its targeting by mesenchymal stem cells (MSCs) and their exosome; current status and prospect
A Nouralishahi, N Fazlinejad, RDC Pecho… - … -Research and Practice, 2023 - Elsevier
Because of their unique capacity for differentiation to a diversity of cell lineages and
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …
Hijacking 5-Fluorouracil Chemoresistance in Triple Negative Breast Cancer via microRNAs-Loaded Chitosan Nanoparticles
Chemotherapy is still the mainstay of treatment for triple-negative breast cancer (TNBC)
patients. Yet only 20% of TNBC patients show a pathologic complete response (pCR) after …
patients. Yet only 20% of TNBC patients show a pathologic complete response (pCR) after …
The Role of microRNAs in Gene Expression and Signaling Response of Tumor Cells to an Acidic Environment
A Riemann, M Rauschner, S Reime… - International Journal of …, 2023 - mdpi.com
Many tumors are characterized by marked extracellular acidosis due to increased glycolytic
metabolism, which affects gene expression and thereby tumor biological behavior. At the …
metabolism, which affects gene expression and thereby tumor biological behavior. At the …
The role of the JAK/STAT3 signaling pathway in acquired corneal diseases
D Song, Q Yang, X Li, K Chen, J Tong… - Experimental Eye …, 2023 - Elsevier
Acquired corneal diseases such as dry eye disease (DED), keratitis and corneal alkali burns
are significant contributors to vision impairment worldwide, and more effective and …
are significant contributors to vision impairment worldwide, and more effective and …
Stem Cell‐Associated Signatures Help to Predict Diagnosis and Prognosis in Ovarian Serous Cystadenocarcinoma
L Li, W Zhang, J Qiu, W Zhang, M Lu… - Stem Cells …, 2023 - Wiley Online Library
Ovarian serous cystadenocarcinoma (OV) is a fatal gynecologic cancer with a five‐year
survival rate of only 46%. Resistance to platinum‐based chemotherapy is a prevalent factor …
survival rate of only 46%. Resistance to platinum‐based chemotherapy is a prevalent factor …