Congenital diaphragmatic hernias: from genes to mechanisms to therapies
G Kardon, KG Ackerman, DJ McCulley… - Disease models & …, 2017 - journals.biologists.com
Congenital diaphragmatic hernias (CDHs) and structural anomalies of the diaphragm are a
common class of congenital birth defects that are associated with significant morbidity and …
common class of congenital birth defects that are associated with significant morbidity and …
Abnormal lung development in congenital diaphragmatic hernia
D Ameis, N Khoshgoo, R Keijzer - Seminars in pediatric surgery, 2017 - Elsevier
The outcomes of patients diagnosed with congenital diaphragmatic hernia (CDH) have
recently improved. However, mortality and morbidity remain high, and this is primarily …
recently improved. However, mortality and morbidity remain high, and this is primarily …
Current concepts on the pathogenesis and etiology of congenital diaphragmatic hernia
JJ Greer - Respiratory Physiology & Neurobiology, 2013 - Elsevier
This review outlines research that has advanced our understanding of the pathogenesis and
etiology of congenital diaphragmatic hernia (CDH). The majority of CDH cases involve …
etiology of congenital diaphragmatic hernia (CDH). The majority of CDH cases involve …
The etiology of congenital diaphragmatic hernia: the retinoid hypothesis 20 years later
JFG Rivas, RD Clugston - Pediatric Research, 2024 - nature.com
Congenital diaphragmatic hernia (CDH) is a severe birth defect and a major cause of
neonatal respiratory distress. Impacting~ 2–3 in 10,000 births, CDH is associated with a high …
neonatal respiratory distress. Impacting~ 2–3 in 10,000 births, CDH is associated with a high …
Retinol status of newborn infants is associated with congenital diaphragmatic hernia
LWJE Beurskens, D Tibboel, J Lindemans… - …, 2010 - publications.aap.org
OBJECTIVE: Genetic analyses in humans suggest a role for retinoid-related genes in the
pathogenesis of congenital diaphragmatic hernia (CDH). The goal of this study was to …
pathogenesis of congenital diaphragmatic hernia (CDH). The goal of this study was to …
Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation
Congenital diaphragmatic hernia (CDH) occurs in 1 in 3,000 newborns. Mortality and
morbidity are due to the amount of pulmonary hypoplasia (PH), the response on artificial …
morbidity are due to the amount of pulmonary hypoplasia (PH), the response on artificial …
The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants
B Schenk, M Weimer, S Bremer, B van der Burg… - Reproductive …, 2010 - Elsevier
ReProTect is a project within the 6th European Framework Program which has developed
alternative methods aimed to reduce or replace animal experimentation in the field of …
alternative methods aimed to reduce or replace animal experimentation in the field of …
Developmental and genetic aspects of congenital diaphragmatic hernia
DCM Veenma, A de Klein, D Tibboel - Pediatric pulmonology, 2012 - Wiley Online Library
Congenital diaphragmatic hernia (CDH) is a frequent occurring cause of neonatal
respiratory distress and occurs 1 in every 3,000 liveborns. Ventilatory support and …
respiratory distress and occurs 1 in every 3,000 liveborns. Ventilatory support and …
Fetal surgery for congenital diaphragmatic hernia is back from never gone
JA Deprest, K Nicolaides, E Gratacos - Fetal diagnosis and therapy, 2011 - karger.com
Over half of the cases of congenital diaphragmatic hernia are picked up prenatally. Prenatal
assessment aims to rule out associated anomalies and to make an individual prognosis …
assessment aims to rule out associated anomalies and to make an individual prognosis …
[HTML][HTML] Polygenic causes of congenital diaphragmatic hernia produce common lung pathologies
PK Donahoe, M Longoni, FA High - The American Journal of Pathology, 2016 - Elsevier
Congenital diaphragmatic hernia (CDH) is one of the most common and lethal congenital
anomalies, and significant evidence is available in support of a genetic contribution to its …
anomalies, and significant evidence is available in support of a genetic contribution to its …