[HTML][HTML] Dynamic control in metabolic engineering: Theories, tools, and applications

CJ Hartline, AC Schmitz, Y Han, F Zhang - Metabolic engineering, 2021 - Elsevier
Metabolic engineering has allowed the production of a diverse number of valuable
chemicals using microbial organisms. Many biological challenges for improving bio …

Refactoring transcription factors for metabolic engineering

C Deng, Y Wu, X Lv, J Li, Y Liu, G Du, J Chen… - Biotechnology …, 2022 - Elsevier
Due to the ability to regulate target metabolic pathways globally and dynamically, metabolic
regulation systems composed of transcription factors have been widely used in metabolic …

De novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts

Y Xu, X Wang, C Zhang, X Zhou, X Xu, L Han… - Nature …, 2022 - nature.com
High-sugar diet causes health problems, many of which can be addressed with the use of
sugar substitutes. Rubusoside and rebaudiosides are interesting molecules, considered the …

Advances in mechanisms and engineering of electroactive biofilms

Z You, J Li, Y Wang, D Wu, F Li, H Song - Biotechnology Advances, 2023 - Elsevier
Electroactive biofilms (EABs) are electroactive microorganisms (EAMs) encased in
conductive polymers that are secreted by EAMs and formed by the accumulation and cross …

[HTML][HTML] Microbial cell factories for green production of vitamins

Y Wang, L Liu, Z Jin, D Zhang - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Vitamins are a group of essential nutrients that are necessary to maintain normal metabolic
activities and optimal health. There are wide applications of different vitamins in food …

[HTML][HTML] Modular engineering for microbial production of carotenoids

C Li, CA Swofford, AJ Sinskey - Metabolic Engineering Communications, 2020 - Elsevier
There is an increasing demand for carotenoids due to their applications in the food, flavor,
pharmaceutical and feed industries, however, the extraction and synthesis of these …

[HTML][HTML] New synthetic biology tools for metabolic control

X Lv, A Hueso-Gil, X Bi, Y Wu, Y Liu, L Liu… - Current Opinion in …, 2022 - Elsevier
In industrial bioprocesses, microbial metabolism dictates the product yields, and therefore,
our capacity to control it has an enormous potential to help us move towards a bio-based …

Genetically encoded biosensors for microbial synthetic biology: From conceptual frameworks to practical applications

W Yu, X Xu, K Jin, Y Liu, J Li, G Du, X Lv, L Liu - Biotechnology Advances, 2023 - Elsevier
Genetically encoded biosensors are the vital components of synthetic biology and metabolic
engineering, as they are regarded as powerful devices for the dynamic control of genotype …

Biosensor-enabled pathway optimization in metabolic engineering

Y Teng, J Zhang, T Jiang, Y Zou, X Gong… - Current opinion in …, 2022 - Elsevier
Microbes can convert inexpensive renewable substrates to valuable metabolites by their
natural metabolic pathways. To maximize the productivity, the pathways yet require further …

[HTML][HTML] Understanding and application of Bacillus nitrogen regulation: a synthetic biology perspective

H He, Y Li, L Zhang, Z Ding, G Shi - Journal of Advanced Research, 2023 - Elsevier
Background Nitrogen sources play an essential role in maintaining the physiological and
biochemical activity of bacteria. Nitrogen metabolism, which is the core of microorganism …