Predicting the functional sites of a protein from its structure, such as the binding sites of small
molecules, other proteins or antibodies, sheds light on its function in vivo. Currently, two …

Proteins are tiny models of biological complexity: specific interactions among their many
amino acids cause proteins to fold into elaborate structures, assemble with other proteins …

Oligomeric proteins are central to cellular life and the duplication and divergence of their
genes is a key driver of evolutionary innovations. The duplication of a gene coding for an …

Protein structures are essential to understanding cellular processes in molecular detail.
While advances in artificial intelligence revealed the tertiary structure of proteins at scale …

Oligomerization is a core structural feature that defines the form and function of many
proteins. Most proteins form molecular complexes; however, there remains a dearth of …

Raising electrocatalysis by rationally devising catalysts plays a core role in almost all
renewable energy conversion and storage systems. The principal catalytic properties can be …

Diverse efforts in protein engineering are beginning to produce novel kinds of symmetric self-
assembling architectures, from protein cages to extended two-dimensional (2D) and three …

Over half the proteins in the E. coli cytoplasm form homo or hetero-oligomeric structures.
Experimentally determined structures are often considered in determining a protein's …

Many enzymes assemble into homomeric protein complexes comprising multiple copies of
one protein. Because structural form is usually assumed to follow function in biochemistry …

A correct assessment of the quaternary structure of proteins is a fundamental prerequisite to
understanding their function, physico-chemical properties and mode of interaction with other …