The protective effect of lipoic acid on selected cardiovascular diseases caused by age‐related oxidative stress

B Skibska, A Goraca - Oxidative Medicine and Cellular …, 2015 - Wiley Online Library
Oxidative stress is considered to be the primary cause of many cardiovascular diseases,
including endothelial dysfunction in atherosclerosis and ischemic heart disease …

[HTML][HTML] Updates on anticancer therapy-mediated vascular toxicity and new horizons in therapeutic strategies

PY Hsu, A Mammadova, N Benkirane-Jessel… - Frontiers in …, 2021 - frontiersin.org
Vascular toxicity is a frequent adverse effect of current anticancer chemotherapies and often
results from endothelial dysfunction. Vascular endothelial growth factor inhibitors (VEGFi) …

[HTML][HTML] Comparison of the effect of two hyaluronic acid preparations on fibroblast and endothelial cell functions related to angiogenesis

V Ciccone, M Zazzetta, L Morbidelli - Cells, 2019 - mdpi.com
Hyaluronic acid (HA) is used in substitutive and aesthetic medicine with various
applications. Ultrapure absorbable HA (Bioregen®) and a mix of reticulated and free low …

H2S dependent and independent anti-inflammatory activity of zofenoprilat in cells of the vascular wall

M Monti, E Terzuoli, M Ziche, L Morbidelli - Pharmacological research, 2016 - Elsevier
Cardiovascular diseases as atherosclerosis are associated to an inflammatory state of the
vessel wall which is accompanied by endothelial dysfunction, and adherence and activation …

[HTML][HTML] Regulatory mechanisms, prophylaxis and treatment of vascular leakage following severe trauma and shock

CY Duan, J Zhang, HL Wu, T Li, LM Liu - Military Medical Research, 2017 - Springer
Vascular leakage, or increased vascular permeability, is a common but important
pathological process for various critical diseases, including severe trauma, shock, sepsis …

Characterization of zofenoprilat as an inducer of functional angiogenesis through increased H2S availability

E Terzuoli, M Monti, V Vellecco, M Bucci… - British journal of …, 2015 - Wiley Online Library
Background and Purpose Hydrogen sulfide (H2S), an endogenous volatile mediator with
pleiotropic functions, promotes vasorelaxation, exerts anti‐inflammatory actions and …

[HTML][HTML] Targeting endothelial cell metabolism for cardio-protection from the toxicity of antitumor agents

L Morbidelli, S Donnini, M Ziche - Cardio-Oncology, 2016 - Springer
The vascular endothelium plays a fundamental role in the maintenance of tissue
homeostasis, regulating local blood flow and other physiological processes …

[HTML][HTML] The nitric oxide donor [zn (pipnono) cl] exhibits antitumor activity through inhibition of epithelial and endothelial mesenchymal transitions

V Ciccone, A Filippelli, C Bacchella, E Monzani… - Cancers, 2022 - mdpi.com
Simple Summary Nitric oxide (NO) plays a critical pathophysiological role in cancer by
modulating several processes, such as angiogenesis, tumor growth, and metastatic …

Functionalised solids delivering bioactive nitric oxide gas for therapeutic applications

ST Gregg, Q Yuan, RE Morris, B Xiao - Materials Today Communications, 2017 - Elsevier
It is well established that nitric oxide is an effective vasodilative, antibacterial and tumoricidal
agent, however its targeted delivery in a controllable manner is challenging but necessary …

Cross-talk between endogenous H2S and NO accounts for vascular protective activity of the metal-nonoate Zn (PipNONO) Cl

M Monti, I Hyseni, A Pacini, E Monzani… - Biochemical …, 2018 - Elsevier
Nitric oxide (NO) and hydrogen sulfide (H 2 S) are now recognized as gaseous transmitters
with many cardiovascular protective properties. The present study concerns the possibility …