Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been
rapidly advanced using large-scale, case–control, candidate gene studies as well as …

Staphylococcus aureus is an important human and livestock pathogen that is well-protected
against environmental insults by a thick cell wall. Accordingly, the wall is a major target of …

Assessment of risk for periodontitis is still in its infancy. Nevertheless, a sufficient amount of
dependable information exists to begin using risk assessment in the day to day practice of …

Atopic dermatitis (AD) is a common, fluctuating skin disease that is often associated with
atopic conditions such as asthma and IgE-mediated food allergy and whose skin lesions are …

Antibodies, otherwise known as immunoglobulins, are glycoproteins which perform a major
role in helping to defend the host against infection. They exist as both membrane bound …

The four subclasses of IgG have different biological activities associated with their Fc
regions. Fc gamma receptors on leucocytes (Fc gamma R) mediate binding and …

A spectrum of in vivo–expressed Staphylococcus aureus antigens was identified by probing
bacteriophage expression libraries of S. aureus with serum samples from infected and …

Two groups of receptors for immunoglobulin G (FcγR) can be distinguished. Endothelial
cells and placental syncytiotrophoblasts express an MHC class I-like FcγR important for …

Human immunoglobulin G (IgG) Fc receptor IIa (Fc gamma RIIa; CD32) is expressed on
phagocytes, triggers phagocytosis, and represents the sole Fc receptor for IgG (Fc gamma …

Disease heterogeneity remains a major challenge for the understanding of systemic lupus
erythematosus (SLE). Recent work has revealed the important role of nonimmune factors in …