FOXM1 and cancer: faulty cellular signaling derails homeostasis
D Kalathil, S John, AS Nair - Frontiers in oncology, 2021 - frontiersin.org
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …
FOXM1: From cancer initiation to progression and treatment
The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …
A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets
DS Castro, B Martynoga, C Parras… - Genes & …, 2011 - genesdev.cshlp.org
Proneural genes such as Ascl1 are known to promote cell cycle exit and neuronal
differentiation when expressed in neural progenitor cells. The mechanisms by which …
differentiation when expressed in neural progenitor cells. The mechanisms by which …
FOXM1: A small fox that makes more tracks for cancer progression and metastasis
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
pathways associated with normal cell homeostasis and disease conditions. Among cancer …
FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression
J Cui, M Shi, D Xie, D Wei, Z Jia, S Zheng, Y Gao… - Clinical Cancer …, 2014 - AACR
Abstract Purpose: The transcription factor Forkhead box protein M1 (FOXM1) plays critical
roles in cancer development and progression. However, the regulatory role and underlying …
roles in cancer development and progression. However, the regulatory role and underlying …
FOXM1 promotes hepatocellular carcinoma progression by regulating KIF4A expression
G Hu, Z Yan, C Zhang, M Cheng, Y Yan… - Journal of Experimental …, 2019 - Springer
Abstract Background Forkhead box M1 (FOXM1) is a proliferation-associated transcription
factor of the forkhead box proteins superfamily, which includes four isoforms FOXM1a, b, c …
factor of the forkhead box proteins superfamily, which includes four isoforms FOXM1a, b, c …
FOX (M1) news—it is cancer
M Halasi, AL Gartel - Molecular cancer therapeutics, 2013 - AACR
FOXM1 is an oncogenic transcription factor of the Forkhead family and it has a well-defined
role in cell proliferation and cell-cycle progression. Expression of FOXM1 is excluded in …
role in cell proliferation and cell-cycle progression. Expression of FOXM1 is excluded in …
A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer
M Shi, J Cui, J Du, D Wei, Z Jia, J Zhang, Z Zhu… - Clinical Cancer …, 2014 - AACR
Purpose: Krüppel-like factor 4 (KLF4) is a transcription factor and putative tumor suppressor.
However, little is known about its effect on aerobic glycolysis in pancreatic tumors …
However, little is known about its effect on aerobic glycolysis in pancreatic tumors …
MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells
Glioblastoma multiforme (GBM) is a life-threatening brain tumor. Accumulating evidence
suggests that eradication of glioma stem-like cells (GSCs) in GBM is essential to achieve …
suggests that eradication of glioma stem-like cells (GSCs) in GBM is essential to achieve …
FoxM1 and Wnt/β-catenin signaling in glioma stem cells
A Gong, S Huang - Cancer research, 2012 - AACR
Cancer stem cells may be responsible for tumor initiation and maintenance. The molecular
mechanisms that control cancer stem cells are related to alterations in various signaling …
mechanisms that control cancer stem cells are related to alterations in various signaling …