Antibiotic use in critical illness

SD Stewart, S Allen - … of Veterinary Emergency and Critical Care, 2019 - Wiley Online Library
Objective To provide a review on the current use of antimicrobials with a discussion on the
pharmacokinetic and pharmacodynamic profiles of antimicrobials in critically ill patients, the …

Pharmacokinetics of conventional and long-acting oxytetracycline preparations in kilis goat

I Aktas, E Yarsan - Frontiers in Veterinary Science, 2017 - frontiersin.org
The pharmacokinetics of conventional and long-acting (LA) oxytetracycline (OTC), widely
used broad-spectrum antibacterial drugs in veterinary medicine, were evaluated in Kilis …

Interindividual variability in plasma concentrations after systemic exposure of swine to dietary doxycycline supplied with and without paracetamol: a population …

JRE Del Castillo, V Laroute, P Pommier… - Journal of animal …, 2006 - academic.oup.com
Anorexigenic substances released during infection may hinder the therapeutic efficacy of in-
feed antibiotics. Paracetamol (acetaminophen; PARA) inhibits the anorexia of infection and …

Serum pharmacokinetics and tissue and milk residues of oxytetracycline in goats following a single intramuscular injection of a long‐acting preparation and milk …

MA Payne, JG Babish, M Bulgin, M Lane… - Journal of veterinary …, 2002 - Wiley Online Library
Separate groups of goats were used to determine drug depletion patterns in serum (n= 10),
tissue (n= 20) and milk (n= 8) following a single intramuscular (im) dose of 20 mg/kg of a …

Pharmacokinetics of ciprofloxacin in normal rabbits and changes observed in induced dehydrated state

S Bashir, M Jamshaid, B Ahmad, J Iqbal - Pakistan Journal of …, 2008 - go.gale.com
The pharmacokinetics of ciprofloxacin following oral administration of a single dose of
20mg/Kg body weight was investigated in normal rabbits and changes were observed in …

Spaceflight pharmacology

V Wotring - Principles of clinical medicine for space flight, 2019 - Springer
Humans who have travelled in space have used medications to ease adaptation to their new
environment (like anti-nausea medications) and to prevent adaptations that could prove …

Effects of water deprivation on the pharmacokinetics of metformin in rats

YH Choi, I Lee, MG Lee - Biopharmaceutics & drug disposition, 2007 - Wiley Online Library
It was reported that metformin was mainly metabolized via hepatic CYP2C11, 2D1 and
3A1/2 in rats, and in a rat model of dehydration, the expressions of hepatic CYP2C11 and …

Kilis keçilerinde geleneksel ve uzun etkili oksitetrasiklin müstahzarlarının farmakokinetiği

İ Aktaş - 2016 - acikbilim.yok.gov.tr
Bu çalışmada, Kilis Keçilerinde veteriner hekimliğinde yaygın şekilde kullanılan ilaçlardan
birisi olan ve geniş etki spektrumlu bir antibakteriyel ilaç olan Oksitetrasiklinin geleneksel …

[图书][B] Translational Pharmacokinetic-Pharmacodynamic Modeling and Simulation in the Development of Spectinamides, a Novel Class of Anti-Tuberculosis Agents

C Rathi - 2017 - search.proquest.com
New chemotherapeutic agents are urgently needed to control the spread of multidrug-
resistant (MDR) and extensively drug-resistant (XDR) forms of tuberculosis, which still …

Absorption

VE Wotring, VE Wotring - Space pharmacology, 2012 - Springer
Absorption is the process by which a drug leaves its site of administration and gets delivered
into the bloodstream. The speed and extent of absorption depend on the route of …