Fatty acid homeostasis in cardiac tissue is characterized by a variety of chemical and
physical processes, the interrelationship and regulating factors of which are only partially …

Plasma membrane blebbing, the development of blister-like or bubble-like protrusions on
the cell surface, is an early morphological alteration of cell injury. During toxic, viral and …

Rationale: Cardiac lipotoxicity, characterized by increased uptake, oxidation, and
accumulation of lipid intermediates, contributes to cardiac dysfunction in obesity and …

The transition from multipotent mesodermal precursor to committed myoblast and its
differentiation into a mature myocyte involve molecular events that enable the cell to activate …

Lipoxygenase Monooxygenase Phospholipase Oxygen Radicals Leukocyte Pathways
Eosinophils Neutrophils Mast Cells Mononuclear Phagocytes Epithelial Cell Pathways …

Physiological cardiac hypertrophy is associated with mitochondrial adaptations that are
characterized by activation of PGC-1α and increased fatty acid oxidative (FAO) capacity. It is …

To investigate the role of cell viability and metabolism on the myocardial kinetics of a new
tracer, technetium-99m-methoxyisobutyl isonitrile (Tc-99m-MIBI), 250 microCi/l Tc-99m-MIBI …

Two distinct morphological patterns of cell death have been recognized, termed necrosis
and apoptosis. Apoptosis, or programmed cell death, occurs in both physiological and …

BACKGROUND A cultured neonatal rat cardiomyocyte model is used to investigate the
expression of the inducible heat shock protein 70 (HSP70i) during hypoxia/reoxygenation …

The heart responds to ischaemic stimuli with release of negative inotropic mediators such as
cytokines, platelet-activating factor, oxygen free radicals, arachidonic acids, nitric oxide …