[HTML][HTML] Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib
Background Loss of heterozygosity (LOH) diminishes genetic diversity within cancer
genomes. A tumour arising in an individual heterozygous for a functional and a loss-of …
genomes. A tumour arising in an individual heterozygous for a functional and a loss-of …
Loss of CYP2D6 sensitizes hepatocellular carcinomas and neuroblastomas to talazoparib
Cancers often have reduced allelic diversity because of loss of heterozygosity (LOH).
Therefore, tumors arising in patients heterozygous for a functional and a loss-of-functon …
Therefore, tumors arising in patients heterozygous for a functional and a loss-of-functon …