Biology and evolution of bacterial toxin–antitoxin systems

D Jurėnas, N Fraikin, F Goormaghtigh… - Nature Reviews …, 2022 - nature.com
Toxin–antitoxin systems are widespread in bacterial genomes. They are usually composed
of two elements: a toxin that inhibits an essential cellular process and an antitoxin that …

Biofilms as promoters of bacterial antibiotic resistance and tolerance

C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Propidium iodide staining underestimates viability of adherent bacterial cells

M Rosenberg, NF Azevedo, A Ivask - Scientific reports, 2019 - nature.com
Combining membrane impermeable DNA-binding stain propidium iodide (PI) with
membrane-permeable DNA-binding counterstains is a widely used approach for bacterial …

Escherichia coli biofilm: development and therapeutic strategies

G Sharma, S Sharma, P Sharma… - Journal of applied …, 2016 - academic.oup.com
Escherichia coli biofilm consists of a bacterial colony embedded in a matrix of extracellular
polymeric substances (EPS) which protects the microbes from adverse environmental …

Bacterial persister cell formation and dormancy

TK Wood, SJ Knabel, BW Kwan - Applied and environmental …, 2013 - Am Soc Microbiol
Bacterial cells may escape the effects of antibiotics without undergoing genetic change;
these cells are known as persisters. Unlike resistant cells that grow in the presence of …

AI-2-mediated signalling in bacteria

CS Pereira, JA Thompson… - FEMS microbiology …, 2013 - academic.oup.com
Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

Intra-and inter-species interactions within biofilms of important foodborne bacterial pathogens

E Giaouris, E Heir, M Desvaux, M Hébraud… - Frontiers in …, 2015 - frontiersin.org
A community-based sessile life style is the normal mode of growth and survival for many
bacterial species. Under such conditions, cell-to-cell interactions are inevitable and …

Indole as an intercellular signal in microbial communities

JH Lee, J Lee - FEMS microbiology reviews, 2010 - academic.oup.com
Bacteria can utilize signal molecules to coordinate their behavior to survive in dynamic
multispecies communities. Indole is widespread in the natural environment, as a variety of …

Optogenetic control of the lac operon for bacterial chemical and protein production

MA Lalwani, SS Ip, C Carrasco-López, C Day… - Nature chemical …, 2021 - nature.com
Control of the lac operon with isopropyl β-d-1-thiogalactopyranoside (IPTG) has been used
to regulate gene expression in Escherichia coli for countless applications, including …