Abstract The Bacillus subtilis strain NDmed was isolated from an endoscope washer-
disinfector in a medical environment. NDmed can form complex macrocolonies with highly …

Abstract Background Sigma factor B (SigB) is the central regulator of the general stress
response in Bacillus subtilis and regulates a group of genes in response to various …

Bacterial genome evolution is characterized by gains, losses, and rearrangements of
functional genetic segments. The extent to which large-scale genomic alterations influence …

In order to adjust to changing environmental conditions, bacteria use nucleotide second
messengers to transduce external signals and translate them into a specific cellular …

Background Bacillus subtilis is a well-established host for a variety of bioproduction
processes, with much interest focused on the production of biosurfactants such as the cyclic …

Motivation High-throughput chemical genomic screens produce informative datasets,
providing valuable insights into unknown gene function on a genome-wide level. However …

Spx is a global transcriptional regulator present in low-GC Gram-positive bacteria, including
the model bacterium Bacillus subtilis and various human pathogens. In B. subtilis, activation …

Bacteria commonly adhere to surfaces where they compete for both space and resources.
Despite the importance of surface growth, it remains largely elusive how bacteria evolve on …

Regulation of transcription is a fundamental process that allows bacteria to respond to
external stimuli with appropriate timing and magnitude of response. In the soil bacterium …

The flagellar motor proteins, MotA and MotB, form a complex that rotates the flagella by
utilizing the proton motive force (PMF) at the bacterial cell membrane. Although PMF affects …