[HTML][HTML] Lung structure and the intrinsic challenges of gas exchange

CCW Hsia, DM Hyde, ER Weibel - Comprehensive physiology, 2016 - ncbi.nlm.nih.gov
Structural and functional complexities of the mammalian lung evolved to meet a unique set
of challenges, namely, the provision of efficient delivery of inspired air to all lung units within …

[HTML][HTML] Pulmonary circulation at exercise

R Naeije, N Chesler - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
The pulmonary circulation is a high flow and low pressure circuit, with an average resistance
of 1 mmHg. min. L− 1 in young adults, increasing to 2.5 mmHg. min. L− 1 over 4–6 decades …

MRI of the lung (2/3). Why… when… how?

J Biederer, M Beer, W Hirsch, J Wild, M Fabel… - Insights into …, 2012 - Springer
Background Among the modalities for lung imaging, proton magnetic resonance imaging
(MRI) has been the latest to be introduced into clinical practice. Its value to replace X-ray …

A century of exercise physiology: key concepts on coupling respiratory oxygen flow to muscle energy demand during exercise

G Ferretti, N Fagoni, A Taboni, G Vinetti… - European Journal of …, 2022 - Springer
After a short historical account, and a discussion of Hill and Meyerhof's theory of the
energetics of muscular exercise, we analyse steady-state rest and exercise as the condition …

High-altitude pulmonary edema

ER Swenson - Textbook of pulmonary vascular disease, 2011 - Springer
High-altitude pulmonary edema (HAPE) is an uncommon form of pulmonary edema that
occurs in healthy individuals within a few days of arrival at altitudes above 2,500–3,000 m …

The gravitational distribution of ventilation-perfusion ratio is more uniform in prone than supine posture in the normal human lung

AC Henderson, RC Sá, RJ Theilmann… - Journal of applied …, 2013 - journals.physiology.org
The gravitational gradient of intrapleural pressure is suggested to be less in prone posture
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …

Lung perfusion disturbances in nonhospitalized post‐COVID with dyspnea—A magnetic resonance imaging feasibility study

JZ Yu, T Granberg, R Shams… - Journal of Internal …, 2022 - Wiley Online Library
Background Dyspnea is common after COVID‐19. Though the underlying mechanisms are
largely unknown, lung perfusion abnormalities could contribute to lingering dyspnea …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

[HTML][HTML] Pulmonary gas exchange and acid-base balance during exercise

MK Stickland, MI Lindinger, IM Olfert… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
As the first step in the oxygen-transport chain, the lung has a critical task: optimizing the
exchange of respiratory gases to maintain delivery of oxygen and the elimination of carbon …

Advances in functional and structural imaging of the human lung using proton MRI

GW Miller, JP Mugler III, RC Sá, TA Altes… - NMR in …, 2014 - Wiley Online Library
The field of proton lung MRI is advancing on a variety of fronts. In the realm of functional
imaging, it is now possible to use arterial spin labeling (ASL) and oxygen‐enhanced …