Understanding how activity patterns in specific neural circuits coordinate an animal's
behavior remains a key area of neuroscience research. Genetic tools and a brain of …

Plasma membrane forms the barrier between the cytoplasm and the environment. Cells
constantly and selectively transport molecules across their plasma membrane without …

The presence of a wound triggers surrounding cells to initiate repair mechanisms, but it is
not clear how cells initially detect wounds. In epithelial cells, the earliest known wound …

We investigated the roles of components of neuronal synapses for development of the
Drosophila air sac primordium (ASP). The ASP, an epithelial tube, extends specialized …

Skin homeostasis is maintained by stem cells, which must communicate to balance their
regenerative behaviors. Yet, how adult stem cells signal across regenerative tissue remains …

To execute the intricate process of development, cells coordinate across tissues and organs
to determine where each cell divides and differentiates. This coordination requires complex …

The robust specification of organ development depends on coordinated cell-cell
communication. This process requires signal integration among multiple pathways, relying …

Epithelial wound healing is an evolutionarily conserved process that requires coordination
across a field of cells. Studies in many organisms have shown that cytosolic calcium levels …

Tissue repair is a complex process that requires effective communication and coordination
between cells across multiple tissues and organ systems. Two of the initial intracellular …

Decoding how tissue properties emerge across multiple spatial and temporal scales from
the integration of local signals is a grand challenge in quantitative biology. For example, the …