Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is
a complex post-translational modification that plays a crucial role in cellular function. It is …

Protein glycosylation is a posttranslational modification that affects more than half of all
known proteins. Glycans covalently bound to biomolecules modulate their functions by both …

Nowadays depression is considered as a systemic illness with different biological
mechanisms involved in its etiology, including inflammatory response, hypothalamic …

This review presents recent progress in employing hydrophilic interaction liquid
chromatography (HILIC) for glycan and glycopeptides analysis. After an introduction of this …

Acute phase proteins (APPs) are a group of circulating plasma proteins which undergo
changes quantitatively or qualitatively at the time of inflammation. Many of these APPs are …

Schizophrenia seems to be a heterogeneous disorder. Emerging evidence indicates that
low level neuroinflammation (LLNI) may not occur infrequently. Many infectious agents with …

Brain extracellular matrix (ECM) is a highly organized system that consists of collagens,
noncollagenous proteins, glycoproteins, hyaluronan, and proteoglycans. Recognized …

Cerebrospinal fluid (CSF) is a clear, transparent fluid derived from blood plasma that
protects the brain and spinal cord against mechanical shock, provides buoyancy, clears …

Glycosylation, the enzymatic attachment of carbohydrates to proteins and lipids, regulates
nearly all cellular processes and is critical in the development and function of the nervous …

Psychotic disorders are severe mental disorders with poorly understood etiology.
Biomarkers in the cerebrospinal fluid (CSF) could provide etiological clues and diagnostic …