[HTML][HTML] A bouquet of DNA structures: Emerging diversity

M Kaushik, S Kaushik, K Roy, A Singh… - … and biophysics reports, 2016 - Elsevier
Structural polymorphism of DNA has constantly been evolving from the time of illustration of
the double helical model of DNA by Watson and Crick. A variety of non-canonical DNA …

Regulatory role of Non-canonical DNA Polymorphisms in human genome and their relevance in Cancer

N Pandya, SR Bhagwat, A Kumar - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
DNA has the ability to form polymorphic structures like canonical duplex DNA and non-
canonical triplex DNA, Cruciform, Z-DNA, G-quadruplex (G4), i-motifs, and hairpin structures …

Structural diversity and specific recognition of four stranded G-quadruplex DNA

M Kaushik, S Kaushik, A Bansal… - Current Molecular …, 2011 - ingentaconnect.com
Structural multitude of nucleic acids serves basis for its multiple merits and applications.
During structural transitions, significant to perform respective cellular functions, these DNA …

Structural properties and binding mechanism of DNA aptamers sensing saliva melatonin for diagnosis and monitoring of circadian clock and sleep disorders

M Pundir, MC De Rosa, L Lobanova… - Analytica Chimica …, 2023 - Elsevier
Circadian desynchrony with the external light-dark cycle influences the rhythmic secretion of
melatonin which is among the first signs of circadian rhythm sleep disorders. An accurate …

Structural polymorphism at LCR and its role in beta-globin gene regulation

S Kukreti, H Kaur, M Kaushik, A Bansal, S Saxena… - Biochimie, 2010 - Elsevier
Information on the secondary structures and conformational manifestations of eukaryotic
DNA and their biological significance with reference to gene regulation and expression is …

Magnesium and molecular crowding of the cosolutes stabilize the i‐motif structure at physiological pH

S Saxena, S Joshi, J Shankaraswamy, S Tyagi… - …, 2017 - Wiley Online Library
Most of the important genomic regions, especially the G, C rich gene promoters, consist of
sequences with potential to form G, C‐tetraplexes on both the DNA strands. In this study, we …

Engineering smart thioflavin T binders with switchable DNA topologies for constructing multiple label-free biosensors

Y Cao, W Li, R Pei - Chemical Engineering Journal, 2024 - Elsevier
Thioflavin T (ThT) has been used as a sensitive fluorescence probe for lighting up nucleic
acids. The binding of ThT is dependent on the structural topologies of DNA sequences. To …

Comparative analysis of human and mouse 3′ Igh regulatory regions identifies distinctive structural features

MA Sepulveda, FE Garrett, A Price-Whelan… - Molecular …, 2005 - Elsevier
Immunoglobulin heavy chain (Igh) locus rearrangements are controlled in part by an∼ 30kb
complex 3′ regulatory region located 3′ of Cα: this region contains several enhancers …

Possibility of an antiparallel (tetramer) quadruplex exhibited by the double repeat of the human telomere

M Kaushik, A Bansal, S Saxena, S Kukreti - Biochemistry, 2007 - ACS Publications
Under physiological concentrations of Na+ and K+, human telomeric DNA can self-associate
into G-quadruplexes. On the basis of circular dichroism, gel electrophoresis, gel filtration …

Pillar [5] arene-induced DNA condensation: Liquid–liquid phase separation in pillar [5] arene-oligonucleotide system

P Skvortsova, D Shurpik, I Stoikov… - Journal of Molecular …, 2022 - Elsevier
The spatial separation of cell components and the simultaneous organization of many
chemical reactions are important constituents of cell functioning. It is achieved through …