Pharmaceutical innovation and advanced biotechnology in the biotech-pharmaceutical industry for antibody–drug conjugate development

Q Ma, P Durga, FXC Wang, HP Yao, MH Wang - Drug Discovery Today, 2024 - Elsevier
Highlights•Antibody-drug conjugate (ADC) is a class of biotherapeutics combining antibody
specificity with the targeted delivery of payloads for the treatment of both cancer and …

P-gp inhibition and enhanced oral bioavailability of amikacin Sulfate: A novel approach using Thiolated Chito-PEGylated Lipidic Hybrids

M Khalid, MA Megahed, A Abdalla, HS El-Sawy… - International Journal of …, 2024 - Elsevier
This study aimed to develop oral lipidic hybrids of amikacin sulfate (AMK), incorporating
thiolated chitosan as a P-glycoprotein (P-gp) inhibitor to enhance intestinal absorptivity and …