Fungal endophytes: Microfactories of novel bioactive compounds with therapeutic interventions; A comprehensive review on the biotechnological developments in the …

A Gupta, V Meshram, M Gupta, S Goyal, KA Qureshi… - Biomolecules, 2023 - mdpi.com
The seminal discovery of paclitaxel from endophytic fungus Taxomyces andreanae was a
milestone in recognizing the immense potential of endophytic fungi as prolific producers of …

Effects of discrete bioactive microbial volatiles on plants and fungi

B Piechulla, MC Lemfack, M Kai - Plant, Cell & Environment, 2017 - Wiley Online Library
Plants live in association with microorganisms, which are well known as a rich source of
specialized metabolites, including volatile compounds. The increasing numbers of …

The emergence of endophytic microbes and their biological promise

G Strobel - Journal of Fungi, 2018 - mdpi.com
As is true with animal species, plants also have an associated microflora including
endophytes as well as microbes associated with the phyllosphere and rhizosphere (plant …

Recent advances in search of bioactive secondary metabolites from fungi triggered by chemical epigenetic modifiers

M Xue, X Hou, J Fu, J Zhang, J Wang, Z Zhao, D Xu… - Journal of Fungi, 2023 - mdpi.com
Genomic analysis has demonstrated that many fungi possess essential gene clusters for the
production of previously unobserved secondary metabolites; however, these genes are …

Resveratrol biosynthesis, optimization, induction, bio-transformation and bio-degradation in mycoendophytes

MA Abo-Kadoum, ME Abouelela, AA Al Mousa… - Frontiers in …, 2022 - frontiersin.org
Resveratrol (3, 4, 5-trihydroxystilbene) is a naturally occurring polyphenolic stilbene
compound produced by certain plant species in response to biotic and abiotic factors …

Antimicrobial activity of endophytic fungi from olive tree leaves

C Malhadas, R Malheiro, JA Pereira… - World Journal of …, 2017 - Springer
In this study, the antimicrobial potential of three fungal endophytes from leaves of Olea
europaea L. was evaluated and the host plant extract effect in the antimicrobial activity was …

Recent advances in inducing endophytic fungal specialized metabolites using small molecule elicitors including epigenetic modifiers

RMK Toghueo, D Sahal, FF Boyom - Phytochemistry, 2020 - Elsevier
Today when the quest of new lead molecules to supply the development pipeline is driving
the course of drug discovery, endophytic fungi with their outstanding biosynthetic potential …

Effects of volatile organic compounds from Streptomyces albulus NJZJSA2 on growth of two fungal pathogens

Y Wu, J Yuan, YE, W Raza, Q Shen… - Journal of basic …, 2015 - Wiley Online Library
A Streptomyces albulus strain NJZJSA2 was isolated from the forest soil sample of Tzu‐chin
Mountain (Nanjing China) and identified based on its morphological and physiological …

Epigenetic modification: A key tool for secondary metabolite production in microorganisms

S Bind, S Bind, AK Sharma, P Chaturvedi - Frontiers in Microbiology, 2022 - frontiersin.org
Microorganisms are stupendous source of secondary metabolites, having significant
pharmaceutical and industrial importance. Genome mining has led to the detection of …

Mangrove-associated fungi: A novel source of potential anticancer compounds

SK Deshmukh, MK Gupta, V Prakash, MS Reddy - Journal of Fungi, 2018 - mdpi.com
Cancer is the second leading cause of death worldwide, and the number of cases is
increasing alarmingly every year. Current research focuses on the development of novel …