Targeting SARS-CoV-2 receptors as a means for reducing infectivity and improving antiviral and immune response: an algorithm-based method for overcoming …
R Gelman, A Bayatra, A Kessler… - Emerging microbes & …, 2020 - Taylor & Francis
The ongoing severe acute respiratory syndrome pandemic caused by the novel coronavirus
2 (SARS-CoV-2) is associated with high morbidity and mortality rates, and it has created a …
2 (SARS-CoV-2) is associated with high morbidity and mortality rates, and it has created a …
Progress and trends in mathematical modelling of influenza A virus infections
Mathematical modelling of influenza A virus infection has seen increased use over the last
several years. Models applied to both in vitro and in vivo data have provided important new …
several years. Models applied to both in vitro and in vivo data have provided important new …
SARS‐CoV‐2 coinfections: Could influenza and the common cold be beneficial?
L Pinky, HM Dobrovolny - Journal of Medical Virology, 2020 - Wiley Online Library
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has
rapidly spread around the world, causing serious illness and death and creating a heavy …
rapidly spread around the world, causing serious illness and death and creating a heavy …
Evolutionary safety of lethal mutagenesis driven by antiviral treatment
Nucleoside analogs are a major class of antiviral drugs. Some act by increasing the viral
mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however …
mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however …
A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract
C Quirouette, NP Younis, MB Reddy… - PLoS computational …, 2020 - journals.plos.org
Within the human respiratory tract (HRT), virus diffuses through the periciliary fluid (PCF)
bathing the epithelium. But virus also undergoes advection: as the mucus layer sitting atop …
bathing the epithelium. But virus also undergoes advection: as the mucus layer sitting atop …
Antiviral drug screen of kinase inhibitors identifies cellular signaling pathways critical for SARS-CoV-2 replication
Emergence of a highly contagious novel coronavirus, SARS-CoV-2 that causes COVID-19,
has precipitated the current global health crisis with over 479,000 deaths and more than 9.3 …
has precipitated the current global health crisis with over 479,000 deaths and more than 9.3 …
Antiviral peptides as anti-influenza agents
M Agamennone, M Fantacuzzi, G Vivenzio… - International Journal of …, 2022 - mdpi.com
Influenza viruses represent a leading cause of high morbidity and mortality worldwide.
Approaches for fighting flu are seasonal vaccines and some antiviral drugs. The …
Approaches for fighting flu are seasonal vaccines and some antiviral drugs. The …
Initial inoculum and the severity of COVID-19: A mathematical modeling study of the dose-response of SARS-CoV-2 infections
B Fain, HM Dobrovolny - Epidemiologia, 2020 - mdpi.com
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) causes a variety of
responses in those who contract the virus, ranging from asymptomatic infections to acute …
responses in those who contract the virus, ranging from asymptomatic infections to acute …
Anti-influenza strategies based on nanoparticle applications
K Wieczorek, B Szutkowska, E Kierzek - Pathogens, 2020 - mdpi.com
Influenza virus has the potential for being one of the deadliest viruses, as we know from the
pandemic's history. The influenza virus, with a constantly mutating genome, is becoming …
pandemic's history. The influenza virus, with a constantly mutating genome, is becoming …
The evolution of Tamiflu synthesis, 20 years on: Advent of enabling technologies the last piece of the puzzle?
CR Sagandira, FM Mathe, U Guyo, P Watts - Tetrahedron, 2020 - Elsevier
Influenza is a serious respiratory disease responsible for significant morbidity and mortality
due to both annual epidemics and pandemics; its treatment involves the use of …
due to both annual epidemics and pandemics; its treatment involves the use of …