Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

DQ Huang, HB El-Serag, R Loomba - Nature reviews Gastroenterology …, 2021 - nature.com
One quarter of the global population is estimated to have nonalcoholic fatty liver disease
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …

[HTML][HTML] Incidence of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression

LA Orci, M Sanduzzi-Zamparelli, B Caballol… - Clinical …, 2022 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) may be a risk factor for
hepatocellular carcinoma (HCC), but the extent of this association still needs to be …

Asia–Pacific Working Party on Non‐alcoholic Fatty Liver Disease guidelines 2017—part 1: definition, risk factors and assessment

VWS Wong, WK Chan, S Chitturi… - Journal of …, 2018 - Wiley Online Library
Since the publication of the guidelines for the assessment and management of non alcoholic
fatty liver disease (NAFLD) by the Asia–Pacific Working Party on NAFLD in 2007, 1 our …

Liver cancer: connections with obesity, fatty liver, and cirrhosis

A Marengo, C Rosso, E Bugianesi - Annual review of medicine, 2016 - annualreviews.org
The burden of hepatocellular carcinoma (HCC), the most common form of liver cancer, is
steadily growing because obesity, type 2 diabetes, and nonalcoholic fatty liver disease …

Nonalcoholic fatty liver disease and hepatocellular carcinoma: Insights in epidemiology, pathogenesis, imaging, prevention and therapy

SA Polyzos, L Chrysavgis, ID Vachliotis… - Seminars in cancer …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is estimated to be the third leading cause of cancer-related
mortality and is characterized by low survival rates. Nonalcoholic fatty liver disease (NAFLD) …

NAFLD, NASH and liver cancer

GA Michelotti, MV Machado, AM Diehl - … reviews Gastroenterology & …, 2013 - nature.com
NAFLD affects a large proportion of the US population and its incidence and prevalence are
increasing to epidemic proportions around the world. As with other liver diseases that cause …

Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review

DL White, F Kanwal, HB El–Serag - Clinical gastroenterology and …, 2012 - Elsevier
BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) has been implicated as a
cause of hepatocellular carcinoma (HCC). We performed a systematic review of …

Circadian homeostasis of liver metabolism suppresses hepatocarcinogenesis

NM Kettner, H Voicu, MJ Finegold, C Coarfa… - Cancer cell, 2016 - cell.com
Chronic jet lag induces spontaneous hepatocellular carcinoma (HCC) in wild-type mice
following a mechanism very similar to that observed in obese humans. The process initiates …

Epidemiology of hepatocellular carcinoma

KJ Lafaro, AN Demirjian… - Surgical Oncology …, 2015 - surgonc.theclinics.com
Primary liver cancer is the fifth most common cancer worldwide and the second leading
cause of cancer mortality. In 2008, there were 749,000 new cases and 695,000 deaths from …

Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

S Watanabe, E Hashimoto, K Ikejima, H Uto… - Journal of …, 2015 - Springer
Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver
disease in industrialized countries worldwide, and has become a serious public health issue …