Insect pest management in the age of synthetic biology

R Mateos Fernández, M Petek… - Plant Biotechnology …, 2022 - Wiley Online Library
Arthropod crop pests are responsible for 20% of global annual crop losses, a figure
predicted to increase in a changing climate where the ranges of numerous species are …

Synthetic biology for plant genetic engineering and molecular farming

Y Wang, GS Demirer - Trends in Biotechnology, 2023 - cell.com
Many efforts have been put into engineering plants to improve crop yields and stress
tolerance and boost the bioproduction of valuable molecules. Yet, our capabilities are still …

[HTML][HTML] Engineering Nicotiana benthamiana as a platform for natural product biosynthesis

D Golubova, C Tansley, H Su, NJ Patron - Current Opinion in Plant Biology, 2024 - Elsevier
Nicotiana benthamiana is a model plant, widely used for research. The susceptibility of
young plants to Agrobacterium tumefaciens has been utilised for transient gene expression …

Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana

QM Dudley, S Jo, DAS Guerrero, M Chhetry… - Communications …, 2022 - nature.com
Monoterpene indole alkaloids (MIAs) are a diverse class of plant natural products that
include a number of medicinally important compounds. We set out to reconstitute the …

The advent of plant cells in bioreactors

F Verdú-Navarro, JA Moreno-Cid, J Weiss… - Frontiers in Plant …, 2023 - frontiersin.org
Ever since agriculture started, plants have been bred to obtain better yields, better fruits, or
sustainable products under uncertain biotic and abiotic conditions. However, a new way to …

Tunable control of insect pheromone biosynthesis in Nicotiana benthamiana

K Kallam, E Moreno‐Giménez… - Plant Biotechnology …, 2023 - Wiley Online Library
Previous work has demonstrated that plants can be used as production platforms for
molecules used in health, medicine, and agriculture. Production has been exemplified in …

Engineering Plant Cell Fates and Functions for Agriculture and Industry

C Tansley, NJ Patron, S Guiziou - ACS Synthetic Biology, 2024 - ACS Publications
Many plant species are grown to enable access to specific organs or tissues, such as seeds,
fruits, or stems. In some cases, a value is associated with a molecule that accumulates in a …

Release of moth pheromone compounds from Nicotiana benthamiana upon transient expression of heterologous biosynthetic genes

YH Xia, BJ Ding, SL Dong, HL Wang, P Hofvander… - BMC biology, 2022 - Springer
Background Using genetically modified plants as natural dispensers of insect pheromones
may eventually become part of a novel strategy for integrated pest management. Results In …

Biosynthesis of insect sex pheromone precursors via engineered β-oxidation in yeast

K Petkevicius, L Wenning, KR Kildegaard… - FEMS Yeast …, 2022 - academic.oup.com
Mating disruption with insect sex pheromones is an attractive and environmentally friendly
technique for pest management. Several Lepidoptera sex pheromones have been produced …

Transcriptional deregulation of stress-growth balance in Nicotiana benthamiana biofactories producing insect sex pheromones

M Juteršek, M Petek, Ž Ramšak… - Frontiers in Plant …, 2022 - frontiersin.org
Plant biofactories are a promising platform for sustainable production of high-value
compounds, among which are insect sex pheromones, a green alternative to conventional …