As an emerging new class, metal nanoparticles and especially silver nanoparticles hold
great potential in the field of cancer biology. Due to cancer-specific targeting, the …

Nanomaterials have emerged as promising candidates for cancer therapy and diagnosis as
they can solve long-term issues such as drug solubility, systemic distribution, tumor acquired …

Cancer nanomedicine is an emerging field of cancer therapeutics. Incidence of
hepatocellular carcinoma (HCC) is increasing worldwide, and currently, it is the second …

Solid tumors often grow in a micro-environment characterized by< 2% O 2 tension. This
condition, together with the aberrant activation of specific oncogenic patwhays, increases …

Cancer is a fatal disease with a complex pathophysiology. Lack of specificity and
cytotoxicity, as well as the multidrug resistance of traditional cancer chemotherapy, are the …

Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …

Purpose Silver nanoparticles (AgNPs) are one of the most commonly investigated
nanomaterials, especially due to their biomedical applications. However, their excellent …

Therapeutic efficacy against cancer relies heavily on the ability of the therapeutic agents to
reach their final targets. The optimal targets of most cancer therapeutic agents are usually …

Multidrug resistance (MDR) in cancer chemotherapy is a growing concern for medical
practitioners. P-glycoprotein (P-gp) overexpression is one of the major reasons for multidrug …

Conventional systems for drug delivery vehicles face many limitations, thus, there have been
an extensive investigation for alternative strategies. In the last decade, nanotechnology had …