The microbiome plays a key role in health and disease, and there has been considerable
interest in therapeutic targeting of the microbiome as well as mining this rich resource in …

Synthetic cannabinoids (SCs) were initially developed as pharmacological tools to probe the
endocannabinoid system and as novel pharmacotherapies, but are now highly abused. This …

Fungi have been extensively studied for their capacity to biotransform a wide range of
natural and xenobiotic compounds. This versatility is a reflection of the broad substrate …

Cunninghamella elegans is a long-established microbial model of mammalian drug and
xenobiotic metabolism enabled by the actions of cytochrome P450 enzymes that are poorly …

Since the discovery over 60 years ago of fluorocortisone's biological properties (9-α-Fluoro
derivatives of cortisone and hydrocortisone; Fried J and Sabo EF, J Am Chem Soc 76: 1455 …

The insecticide λ-cyhalothrin was incubated with planktonic and biofilm cultures of the
fungus Cunninghamella elegans. 19 F nuclear magnetic resonance spectroscopy …

The goal of the biotransformation process is to develop structural changes and generate
new chemical compounds, which can occur naturally in mammalian and microbial …

The present study was conducted to evaluate the potential of the fungus Cunninghamella
elegans for simultaneous decolourisation of a triphenylmethane dye malachite green (MG) …

In this perspective, we highlight recent examples and trends in metabolic engineering and
synthetic biology that demonstrate the synthetic potential of enzyme and pathway …

The fungus Cunninghamella elegans is recognised as a microbial model of mammalian
drug metabolism owing to its ability to catabolise xenobiotic compounds in an analogous …