Multimodal biomedical AI
The increasing availability of biomedical data from large biobanks, electronic health records,
medical imaging, wearable and ambient biosensors, and the lower cost of genome and …
medical imaging, wearable and ambient biosensors, and the lower cost of genome and …
Timing of lifespan influences on brain and cognition
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
Association of healthful plant-based diet adherence with risk of mortality and major chronic diseases among adults in the UK
AS Thompson, A Tresserra-Rimbau… - JAMA Network …, 2023 - jamanetwork.com
Importance Plant-based diets have gained popularity for both environmental and health
reasons, but a comprehensive assessment of their quality in relation to risk of mortality and …
reasons, but a comprehensive assessment of their quality in relation to risk of mortality and …
Accelerated biological aging and risk of depression and anxiety: evidence from 424,299 UK Biobank participants
Abstract Theory predicts that biological processes of aging may contribute to poor mental
health in late life. To test this hypothesis, we evaluated prospective associations between …
health in late life. To test this hypothesis, we evaluated prospective associations between …
Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort …
Objective To compare established associations between risk factors and mortality in UK
Biobank, a study with an exceptionally low rate of response to its baseline survey, against …
Biobank, a study with an exceptionally low rate of response to its baseline survey, against …
Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population
Biomarkers of low-grade inflammation have been associated with susceptibility to a severe
infectious disease course, even when measured prior to disease onset. We investigated …
infectious disease course, even when measured prior to disease onset. We investigated …
Genetic analyses identify widespread sex-differential participation bias
N Pirastu, M Cordioli, P Nandakumar, G Mignogna… - Nature Genetics, 2021 - nature.com
Genetic association results are often interpreted with the assumption that study participation
does not affect downstream analyses. Understanding the genetic basis of participation bias …
does not affect downstream analyses. Understanding the genetic basis of participation bias …
Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort …
Objectives We aimed to investigate demographic, lifestyle, socioeconomic and clinical risk
factors for COVID-19, and compared them to risk factors for pneumonia and influenza in UK …
factors for COVID-19, and compared them to risk factors for pneumonia and influenza in UK …
GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer
Genetic studies have examined body-shape measures adjusted for body mass index (BMI),
while allometric indices are additionally adjusted for height. We performed the first genome …
while allometric indices are additionally adjusted for height. We performed the first genome …
[HTML][HTML] Is cohort representativeness passé? Poststratified associations of lifestyle risk factors with mortality in the UK Biobank
Background: The UK Biobank (UKB) has been used widely to examine associations
between lifestyle risk factors and mortality outcomes. It is unknown whether the extremely …
between lifestyle risk factors and mortality outcomes. It is unknown whether the extremely …