Hypothalamic AMPK: a canonical regulator of whole-body energy balance

M Lopez, R Nogueiras, M Tena-Sempere… - Nature Reviews …, 2016 - nature.com
AMP-activated protein kinase (AMPK) has a major role in the modulation of energy balance.
AMPK is activated in conditions of low energy, increasing energy production and reducing …

High dietary fructose: direct or indirect dangerous factors disturbing tissue and organ functions

DM Zhang, RQ Jiao, LD Kong - Nutrients, 2017 - mdpi.com
High dietary fructose is a major contributor to insulin resistance and metabolic syndrome,
disturbing tissue and organ functions. Fructose is mainly absorbed into systemic circulation …

[HTML][HTML] Heat stress alters muscle protein and amino acid metabolism and accelerates liver gluconeogenesis for energy supply in broilers

B Ma, L Zhang, J Li, T Xing, Y Jiang, F Gao - Poultry science, 2021 - Elsevier
Heat stress impairs growth performance and alters body protein and amino acid metabolism.
This study was investigated to explore how body protein and amino acid metabolism …

Metabolic control through glucocorticoid hormones: an update

AJ Rose, S Herzig - Molecular and cellular endocrinology, 2013 - Elsevier
In the past decades, glucocorticoid (GC) hormones and their cognate, intracellular receptor,
the glucocorticoid receptor (GR), have been well established as critical checkpoints in …

Betaine prevented fructose-induced NAFLD by regulating LXRα/PPARα pathway and alleviating ER stress in rats

CX Ge, R Yu, MX Xu, PQ Li, CY Fan, JM Li… - European journal of …, 2016 - Elsevier
Betaine has been proven effective in treating nonalcoholic fatty liver disease (NAFLD) in
animal models, however, its molecular mechanisms remain elusive. The aims of this study …

High-fructose diet during periadolescent development increases depressive-like behavior and remodels the hypothalamic transcriptome in male rats

CS Harrell, J Burgado, SD Kelly, ZP Johnson… - …, 2015 - Elsevier
Fructose consumption, which promotes insulin resistance, hypertension, and dyslipidemia,
has increased by over 25% since the 1970s. In addition to metabolic dysregulation, fructose …

Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice

MC Calixto, L Lintomen, DM André, LO Leiria… - PloS one, 2013 - journals.plos.org
A positive relationship between obesity and asthma has been well documented. The AMP-
activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin …

High fructose diet-induced metabolic syndrome: pathophysiological mechanism and treatment by traditional Chinese medicine

Y Pan, LD Kong - Pharmacological research, 2018 - Elsevier
Fructose is a natural monosaccharide broadly used in modern society. Over the past few
decades, epidemiological studies have demonstrated that high fructose intake is an …

Insights into the hexose liver metabolism—glucose versus fructose

B Geidl-Flueck, PA Gerber - Nutrients, 2017 - mdpi.com
High-fructose intake in healthy men is associated with characteristics of metabolic
syndrome. Extensive knowledge exists about the differences between hepatic fructose and …

Glucocorticoid hormones and energy homeostasis

RM de Guia, AJ Rose, S Herzig - Hormone molecular biology and …, 2014 - degruyter.com
Glucocorticoids (GC) and their cognate intracellular receptor, the glucocorticoid receptor
(GR), have been characterised as critical checkpoints in the endocrine control of energy …