The pathophysiology of gestational diabetes mellitus

JF Plows, JL Stanley, PN Baker, CM Reynolds… - International journal of …, 2018 - mdpi.com
Gestational diabetes mellitus (GDM) is a serious pregnancy complication, in which women
without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In …

Recently updated global diabetic retinopathy screening guidelines: commonalities, differences, and future possibilities

T Das, B Takkar, S Sivaprasad, T Thanksphon… - Eye, 2021 - nature.com
Diabetic retinopathy (DR) is a global health burden. Screening for sight-threatening DR
(STDR) is the first cost-effective step to decrease this burden. We analyzed the similarities …

Esaxerenone (CS-3150) in patients with type 2 diabetes and microalbuminuria (ESAX-DN): phase 3 randomized controlled clinical trial

S Ito, N Kashihara, K Shikata, M Nangaku… - Clinical Journal of the …, 2020 - journals.lww.com
Results Overall, 49 (22%) and nine (4%) patients in the esaxerenone and placebo groups,
respectively, achieved urinary albumin-to-creatinine ratio remission (absolute difference …

Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (PIONEER 9): a 52-week, phase 2/3a, randomised …

Y Yamada, H Katagiri, Y Hamamoto… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Given the unique phenotype of type 2 diabetes in Japanese patients, novel
therapies such as oral semaglutide require evaluation in this population. PIONEER 9 aimed …

Safety and efficacy of oral semaglutide versus dulaglutide in Japanese patients with type 2 diabetes (PIONEER 10): an open-label, randomised, active-controlled …

D Yabe, J Nakamura, H Kaneto… - The Lancet Diabetes & …, 2020 - thelancet.com
Background New glucose-lowering medications need to be investigated in east Asian
populations, as the clinical characteristics of type 2 diabetes differ between western and east …

Retrospective nationwide study on the trends in first‐line antidiabetic medication for patients with type 2 diabetes in Japan

R Bouchi, T Sugiyama, A Goto, K Imai… - Journal of Diabetes …, 2022 - Wiley Online Library
Abstract Aims/Introduction To investigate the national trend in the prescription of first‐line
non‐insulin antidiabetic agents and total medical costs (TMCs) after prescribing the drug in …

Efficacy and safety of imeglimin monotherapy versus placebo in Japanese patients with type 2 diabetes (TIMES 1): a double-blind, randomized, placebo-controlled …

J Dubourg, P Fouqueray, C Thang, JM Grouin… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE The aim of this study was to investigate the efficacy and safety of imeglimin, the
first in a new class of oral antidiabetic agent, in Japanese patients with type 2 diabetes …

Flash glucose monitoring helps achieve better glycemic control than conventional self-monitoring of blood glucose in non-insulin-treated type 2 diabetes: a …

E Wada, T Onoue, T Kobayashi, T Handa… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction The present study aimed to evaluate the effects of flash glucose monitoring
(FGM) and conventional self-monitoring of blood glucose (SMBG) on glycemic control in …

JCS 2018 guideline on diagnosis of chronic coronary heart diseases

M Yamagishi, N Tamaki, T Akasaka, T Ikeda… - Circulation …, 2021 - jstage.jst.go.jp
Objectives”, explains how to select and use various test methods for evaluating disease
states, the prognosis, and the effects of treatment. References to the literature published …

Efficacy and safety of esaxerenone (CS-3150) for the treatment of type 2 diabetes with microalbuminuria: a randomized, double-blind, placebo-controlled, phase II trial

S Ito, K Shikata, M Nangaku, Y Okuda… - Clinical Journal of the …, 2019 - journals.lww.com
Results Esaxerenone treatment at 1.25, 2.5, and 5 mg/d significantly reduced urinary
albumin-to-creatinine ratio by the end of treatment (38%, 50%, and 56%, respectively) …