Cell microenvironment engineering and monitoring for tissue engineering and regenerative medicine: the recent advances

J Barthes, H Özçelik, M Hindié… - BioMed research …, 2014 - Wiley Online Library
In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of
the cells have a direct effect on cells' behaviour and subsequently on clinical outcomes …

Droplet microfluidics for synthetic biology

PC Gach, K Iwai, PW Kim, NJ Hillson, AK Singh - Lab on a Chip, 2017 - pubs.rsc.org
Synthetic biology is an interdisciplinary field that aims to engineer biological systems for
useful purposes. Organism engineering often requires the optimization of individual genes …

Microfluidic formulation of anticancer peptide loaded ZIF-8 nanoparticles for the treatment of breast cancer

J Qiu, MA Tomeh, Y Jin, B Zhang, X Zhao - Journal of Colloid and Interface …, 2023 - Elsevier
Anticancer peptides (ACPs) are promising antitumor drugs owning to their great cancer cell
targeting and anticancer effects as well as low drug resistance. However, many of the ACPs …

Expanding CAR-T cell immunotherapy horizons through microfluidics

H Kim, S Kim, H Lim, AJ Chung - Lab on a Chip, 2024 - pubs.rsc.org
Chimeric antigen receptor (CAR)-T cell therapies have revolutionized cancer treatment,
particularly in hematological malignancies. However, their application to solid tumors is …

Microfluidic approaches for gene delivery and gene therapy

J Kim, I Hwang, D Britain, TD Chung, Y Sun, DH Kim - Lab on a Chip, 2011 - pubs.rsc.org
Recent advances in microfluidics have created new and exciting prospects for gene delivery
and therapy. The micro-scaled environment within microfluidic systems enables precise …

Microfluidic tools toward industrial biotechnology

AF Oliveira, ACSN Pessoa, RG Bastos… - Biotechnology …, 2016 - Wiley Online Library
Microfluidics is a technology that operates with small amounts of fluids and makes possible
the investigation of cells, enzymes, and biomolecules and encapsulation of biocatalysts in a …

Microfluidic bioreactors for cell culturing: a review

G Pasirayi, V Auger, SM Scott… - Micro and …, 2011 - ingentaconnect.com
The use of microfluidic bioreactor platforms for cell culturing holds considerable promise for
a range of fields which include drug discovery, tissue engineering, bioprocessing …

Modeling combined effects of temperature and structure on competition and growth of multispecies biofilms in microbioreactors

M Aghajani Delavar, J Wang - Industrial & Engineering Chemistry …, 2020 - ACS Publications
It is a well-known challenge to simulate competition and growth of multiple microorganisms
in microbioreactors because of complex interactions among microorganisms, substrate …

Bioengineered baculoviruses as new class of therapeutics using micro and nanotechnologies: principles, prospects and challenges

A Paul, A Hasan, L Rodes, M Sangaralingam… - Advanced Drug Delivery …, 2014 - Elsevier
Designing a safe and efficient gene delivery system is required for success of gene therapy
trials. Although a wide variety of viral, non-viral and polymeric nanoparticle based careers …

Biological implications of polymeric microdevices for live cell assays

D Wlodkowic, S Faley, J Skommer… - Analytical …, 2009 - ACS Publications
Lab-on-a-chip technologies have the potential to deliver significant technological advances
in modern biomedicine, through the ability to provide appropriate low-cost …