Stevia Genus: Phytochemistry and Biological Activities Update

J Borgo, LC Laurella, F Martini, CAN Catalán… - Molecules, 2021 - mdpi.com
The Stevia genus (Asteraceae) comprises around 230 species, distributed from the southern
United States to the South American Andean region. Stevia rebaudiana, a Paraguayan herb …

The impact of polyphenolics in the management of breast cancer: mechanistic aspects and recent patents

HAS El-Nashar, SH Aly, A Ahmadi… - Recent Patents on Anti …, 2022 - ingentaconnect.com
Background: Breast cancer is the most frequently diagnosed type of cancer in women,
accounting for 2.1 million cases, and stands as the fifth leading cause of death. Several …

Comparative Assessment of the Antioxidant and Anticancer Activities of Plicosepalus acacia and Plicosepalus curviflorus: Metabolomic Profiling and In Silico Studies

EE Eltamany, MS Goda, MS Nafie, AM Abu-Elsaoud… - Antioxidants, 2022 - mdpi.com
This study presents a comparison between two mistletoe plants—P. acacia and P.
curviflorus—regarding their total phenolic contents and antioxidant and anticancer activities …

Chemical Profiling, Antioxidant, Cytotoxic Activities and Molecular Docking Simulation of Carrichtera annua DC. (Cruciferae)

EE Eltamany, SS Elhady, HA Ahmed, JM Badr… - Antioxidants, 2020 - mdpi.com
Our investigation intended to analyze the chemical composition and the antioxidant activity
of Carrichtera annua and to evaluate the antiproliferative effect of C. annua crude and …

Pedoclimatic Conditions Influence the Morphological, Phytochemical and Biological Features of Mentha pulegium L.

L Cornara, F Sgrò, FM Raimondo, M Ingegneri… - Plants, 2022 - mdpi.com
In this study, Mentha pulegium leaves and flowers harvested in three different Sicilian areas
were investigated from a micromorphological, phytochemical and biological point of view …

In silico evaluation of different flavonoids from medicinal plants for their potency against SARS-CoV-2

HRA El-Mageed, DA Abdelrheem, MO Rafi, MT Sarker… - Biologics, 2021 - mdpi.com
The ongoing pandemic situation of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) poses a global threat to both the world economy and public …

Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets

TT Odunitan, OA Saibu, BT Apanisile… - Computers in Biology …, 2023 - Elsevier
Computational modelling remains an indispensable technique in drug discovery. With
myriad of high computing resources, and improved modelling algorithms, there has been a …

[HTML][HTML] Opportunities, obstacles and current challenges of flavonoids for luminal and triple-negative breast cancer therapy

VS Vachetta, M Marder, MF Troncoso… - European Journal of …, 2022 - Elsevier
Flavonoids are a large group of polyphenols with numerous biological effects on cancer
cells. They have been shown to affect proliferation via cell cycle arrest, apoptosis and …

Chemical Composition, Antibacterial Screening and Cytotoxic Activity of Chiliadenus antiatlanticus (Asteraceae) Essential Oil

M El Yaagoubi, S Ortiz, H Mechqoq… - Chemistry & …, 2021 - Wiley Online Library
The chemical composition and in vitro antibacterial and cytotoxic activities of the essential oil
(EO) of Chiliadenus antiatlanticus (Emb. & Maire) Gómiz, an asteraceous species endemic …

VEGFR-Mediated Cytotoxic Activity of Pulicaria undulata Isolated Metabolites: A Biological Evaluation and In Silico Study

SS Elhady, RFA Abdelhameed, SH Zekry, AK Ibrahim… - Life, 2021 - mdpi.com
Natural products play a remarkable role not only in the synthesis, design, and discovery of
new drugs but also as the most prominent source of drugs and bioactive substances. Adding …