The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has
advanced our understanding of the pathogenesis of disease and provided valuable insights …

The combination of immunotherapy and molecular targeted therapy exhibits promising
therapeutic efficacy in hepatocellular carcinoma (HCC), but the underlying mechanism is still …

Colon adenocarcinoma (COAD) is the primary factor responsible for cancer-related
mortalities in western countries, and its development and progression are affected by altered …

Purpose: Breast cancer is a highly heterogeneous malignancy, seriously threatening female
health worldwide and inducing higher mortalities. Few have the studies evaluated Fms-like …

Introduction Breast cancer (BC) is now the most common type of cancer in women.
Disulfidptosis is a new regulation of cell death (RCD). RCD dysregulation is causally linked …

Abstract Although N7-methylguanosine (m7G) is one of the most frequent RNA
modifications, it has received little attention. Adrenocortical carcinoma (ACC) is a highly …

Copper-dependent cell death, called cuproptosis, is connected to tumor development,
prognosis, and the immune response. Nevertheless, the function of cuproptosis-related …

Cuprotosis, an emerging mode of cell death, has recently caught the attention of researchers
worldwide. However, its impact on low-grade glioma (LGG) patients has not been fully …

Abstract Background Immune checkpoint inhibitors (ICIs) have shown numerous clinical
benefits in multiple cancer types, but good predictive biomarkers are severely lacking …

Background Chemoresistance is a major hurdle to improving the prognosis of pancreatic
cancer (PC). This study aimed to identify key genes regulating chemoresistance and …