Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Antimicrobial peptides: a new frontier in antifungal therapy

G Buda De Cesare, SA Cristy, DA Garsin, MC Lorenz - MBio, 2020 - Am Soc Microbiol
Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …

[HTML][HTML] Synthetic antimicrobial peptides: Characteristics, design, and potential as alternative molecules to overcome microbial resistance

PG Lima, JTA Oliveira, JL Amaral, CDT Freitas… - Life Sciences, 2021 - Elsevier
Recently, the dramatic emergence of antimicrobial resistance has received attention from
World Health Organization. Synthetic antimicrobial peptides (SAMPs) are considered new …

Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

F Guilhelmelli, N Vilela, P Albuquerque… - Frontiers in …, 2013 - frontiersin.org
Antimicrobial peptides (AMPs) are natural antibiotics produced by various organisms such
as mammals, arthropods, plants, and bacteria. In addition to antimicrobial activity, AMPs can …

Peptides, new tools for plant protection in eco-agriculture

YM Zhang, DX Ye, Y Liu, XY Zhang, YL Zhou… - Advanced …, 2023 - Elsevier
As important physiological regulators, peptides have been used in many fields including
medicine, cosmetics, healthcare products, animal nutrition and health, and plant nutrition …

The Mechanism of Antifungal Action of Essential Oil from Dill (Anethum graveolens L.) on Aspergillus flavus

J Tian, X Ban, H Zeng, J He, Y Chen, Y Wang - PloS one, 2012 - journals.plos.org
The essential oil extracted from the seeds of dill (Anethum graveolens L.) was demonstrated
in this study as a potential source of an eco-friendly antifungal agent. To elucidate the …

The evolution, function and mechanisms of action for plant defensins

K Parisi, TMA Shafee, P Quimbar… - Seminars in cell & …, 2019 - Elsevier
Plant defensins are an extensive family of small cysteine rich proteins characterised by a
conserved cysteine stabilised alpha beta protein fold which resembles the structure of insect …

Membrane-interacting antifungal peptides

C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Antifungal peptides: To be or not to be membrane active

M Rautenbach, AM Troskie, JA Vosloo - Biochimie, 2016 - Elsevier
Most antifungal peptides (AFPs), if not all, have membrane activity, while some also have
alternative targets. Fungal membranes share many characteristics with mammalian …

The role of antimicrobial peptides in plant immunity

ML Campos, CM de Souza… - Journal of …, 2018 - academic.oup.com
Selective pressure imposed by millions of years of relentless biological attack has led to the
development of an extraordinary array of defense strategies in plants. Among these …