Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and cognitive impairment. It is caused by synaptic failure and excessive …

This review covers the pathogenesis of ischemic stroke and future directions regarding
therapeutic options after injury. Ischemic stroke is a devastating disease process affecting …

Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside
within distinct regions of the brain. This phenomenon was first described over 50 years ago …

Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …

In this review, we consider the evidence that a reduction in neurogenesis underlies aging-
related cognitive deficits and impairments in disorders such as Alzheimer's disease (AD) …

Neurogenesis occurs in the adult mammalian brain and may play roles in learning and
memory processes and recovery from injury, suggesting that abnormalities in neural …

Ischemic stroke is caused by the interruption of cerebral blood flow that leads to brain
damage with long-term sensorimotor deficits. Stem cell transplantation may recover …

Stem cell therapies have been proposed as a treatment option for neurodegenerative
diseases, but the best stem cell source and therapeutic efficacy for neuroregeneration …

Stem cell–based therapy has been proposed as a potential means of treatment for a variety
of brain disorders. Because ethical and technical issues have so far limited the clinical …

Stem cells offer an enormous pool of resources for the understanding of the human body.
One proposed use of stem cells has been as an autologous therapy. The use of stem cells …