Non-ionic surfactants for stabilization of polymeric nanoparticles for biomedical uses
H Cortés, H Hernández-Parra, SA Bernal-Chávez… - Materials, 2021 - mdpi.com
Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …
formation methods and to preserve the stability of carriers in liquid media. The deposition of …
Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …
the pharmaceutical industry with the development of novel drug delivery systems that …
[HTML][HTML] Paclitaxel and naringenin-loaded solid lipid nanoparticles surface modified with cyclic peptides with improved tumor targeting ability in glioblastoma …
L Wang, X Wang, L Shen, M Alrobaian… - Biomedicine & …, 2021 - Elsevier
The present work describes the systematic development of paclitaxel and naringenin-loaded
solid lipid nanoparticles (SLNs) for the treatment of glioblastoma multiforme (GBM). So far …
solid lipid nanoparticles (SLNs) for the treatment of glioblastoma multiforme (GBM). So far …
Quality by design driven development of resveratrol loaded ethosomal hydrogel for improved dermatological benefits via enhanced skin permeation and retention
Resveratrol is a potent anti-oxidant agent and can be used for the effective management of
different skin conditions like extrinsic skin ageing, psoriasis, etc. The objective of this …
different skin conditions like extrinsic skin ageing, psoriasis, etc. The objective of this …
QbD based exploration of resveratrol loaded polymeric micelles based carbomer gel for topical treatment of plaque psoriasis: In vitro, ex vivo and in vivo studies
Topical delivery of Resveratrol is a safe method for treatment of plaque psoriasis which
could overcome the existing limitations. However, poor permeability of biomolecules through …
could overcome the existing limitations. However, poor permeability of biomolecules through …
Nanostructured lipid carrier system: A compendium of their formulation development approaches, optimization strategies by quality by design, and recent applications …
The lipid-based colloidal carriers, such as nanostructured lipid carriers (NLCs), solid lipid
nanoparticles (SLNs), nanocapsules, liposomes, and microemulsion, are the latest and …
nanoparticles (SLNs), nanocapsules, liposomes, and microemulsion, are the latest and …
Paclitaxel-loaded nanolipidic carriers with improved oral bioavailability and anticancer activity against human liver carcinoma
Harshita, MA Barkat, M Rizwanullah, S Beg… - AAPS …, 2019 - Springer
The poorly water-soluble chemotherapeutic agents, paclitaxel (PTX), exhibit serious clinical
side effects upon oral administration due to poor aqueous solubility and a high degree of …
side effects upon oral administration due to poor aqueous solubility and a high degree of …
Box–Behnken designs and their applications in pharmaceutical product development
S Beg, S Akhter - Design of Experiments for Pharmaceutical Product …, 2021 - Springer
Abstract Box–Behnken designs (BBDs) are the very efficient response surface design which
provides information exclusively on the effect of experiment variables and overall …
provides information exclusively on the effect of experiment variables and overall …
QbD aided development of ibrutinib-loaded nanostructured lipid carriers aimed for lymphatic targeting: evaluation using chylomicron flow blocking approach
N Rangaraj, SR Pailla, S Shah, S Prajapati… - Drug delivery and …, 2020 - Springer
Ibrutinib (IBR) is the choice of drug for the treatment of chronic lymphocytic leukaemia (CLL)
and mantle cell lymphoma (MCL). IBR has low oral bioavailability of 2.9% owing to its high …
and mantle cell lymphoma (MCL). IBR has low oral bioavailability of 2.9% owing to its high …
QbD applications for the development of nanopharmaceutical products
Quality cannot be tested in final product rather it must be maintained within the process so
judiciously planned approaches will improve the performance of process as well as final …
judiciously planned approaches will improve the performance of process as well as final …