Epidemiological, therapeutic, and survival trends in malignant pleural mesothelioma: A review of the National Cancer Database

P Bou‐Samra, A Chang, F Azari, G Kennedy… - Cancer …, 2023 - Wiley Online Library
Background Malignant pleural mesothelioma (MPM) is an aggressive cancer of the cells
lining the pleural cavity with a low overall incidence. The National Cancer Database (NCDB) …

[HTML][HTML] Hyperprogression in advanced melanoma is not restricted to immunotherapy

M Fournier, L Mortier, O Dereure, S Dalac… - European Journal of …, 2023 - Elsevier
Background The definition of hyperprogressive disease (HPD) is controversial in the
literature and has not been widely described in melanoma. The aim of this study was to …

Metastatic lymph node targeted CTLA4 blockade: a potent intervention for local and distant metastases with minimal ICI-induced pneumonia

R Mishra, A Sukhbaatar, S Mori, T Kodama - Journal of Experimental & …, 2023 - Springer
Background Immune checkpoint blockade (ICB) elicits a strong and durable therapeutic
response, but its application is limited by disparate responses and its associated immune …

Exploring the molecular players behind the potentiation of chemotherapy effects by durvalumab in lung adenocarcinoma cell lines

M Saar, J Jaal, A Meltsov, T Laasfeld, H Lust… - Pharmaceutics, 2023 - mdpi.com
Immune checkpoint inhibitors are increasingly used in combination with chemotherapy for
the treatment of non-small cell lung cancer, yet the success of combination therapies is …

Noninvasive radiomic biomarkers for predicting pseudoprogression and hyperprogression in patients with non-small cell lung cancer treated with immune checkpoint …

Y Li, P Wang, J Xu, X Shi, T Yin, F Teng - OncoImmunology, 2024 - Taylor & Francis
This study aimed to develop a computed tomography (CT)-based radiomics model capable
of precisely predicting hyperprogression and pseudoprogression (PP) in patients with non …

Atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma progressing after molecular targeted therapy: A multicenter prospective …

R Sugimoto, T Satoh, A Ueda, T Senju, Y Tanaka… - Medicine, 2022 - journals.lww.com
Atezolizumab plus bevacizumab treatment for unresectable hep... : Medicine Atezolizumab
plus bevacizumab treatment for unresectable hepatocellular carcinoma progressing after …

[HTML][HTML] Impact of performance status on survival outcomes and health care utilization in patients with advanced NSCLC treated with immune checkpoint inhibitors

DE Meyers, M Pasternak, S Dolter, HAI Grosjean… - JTO Clinical and …, 2023 - Elsevier
Introduction Landmark trials testing immune checkpoint inhibitors (ICIs) in advanced NSCLC
are difficult to extrapolate to real-world practice given the exclusion of patients with poor …

The pattern of tumor progression on first-line immune checkpoint inhibitor-based systemic therapy for Chinese advanced hepatocellular carcinoma–CLEAP 004 study

CX Yang, YX Pan, F Ye, XD Zhu, J Xue, X Li… - Frontiers in …, 2024 - frontiersin.org
Background For decades, stratification criteria for first-line clinical studies have been highly
uniform. However, there is no principle or consensus for restratification after systemic …

Revisiting EXTREME in the Immuno-Oncology Era: How to Improve Its Outcomes

P Szturz, JB Vermorken - The Oncologist, 2021 - academic.oup.com
The choice of first-line palliative treatment has always been one of the crucial decisions in
the management of patients with recurrent and/or metastatic squamous cell carcinoma of the …

Role of primary care in detection of subsequent primary cancers

KJ Jackson, KR Emmons, DM Nickitas - The Journal for Nurse Practitioners, 2022 - Elsevier
Significant advances in the detection and treatment of initial cancers increase the likelihood
of life-threatening subsequent primary cancers, particularly for long-term survivors. A brief …